Detailed information NTG0862346

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: WCU14_RS18530
• Genome accession: NZ_CP147625
• Coordinates: 3957539..3958819 (-)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain GN06858
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3952539..3963819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WCU14_RS18520 (WCU14_18520)	hupB	3954603..3954875 (-)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-
WCU14_RS18525 (WCU14_18525)	lon	3955011..3957407 (-)	2397	WP_023081791.1	endopeptidase La	-
WCU14_RS18530 (WCU14_18530)	clpX	3957539..3958819 (-)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
WCU14_RS18535 (WCU14_18535)	clpP	3958924..3959565 (-)	642	WP_003098129.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
WCU14_RS18540 (WCU14_18540)	tig	3959659..3960969 (-)	1311	WP_023081792.1	trigger factor	-
WCU14_RS18545 (WCU14_18545)	parR	3961201..3961908 (+)	708	WP_003098126.1	response regulator transcription factor ParR	-
WCU14_RS18550 (WCU14_18550)	parS	3961909..3963195 (+)	1287	WP_003087912.1	sensor histidine kinase ParS	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=862346 WCU14_RS18530 WP_003087924.1 3957539..3958819(-) (clpX) [Pseudomonas aeruginosa strain GN06858]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=862346 WCU14_RS18530 WP_003087924.1 3957539..3958819(-) (clpX) [Pseudomonas aeruginosa strain GN06858]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAACTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATTTCCCGGAAATCGGACAACCCCTCCATCACTCGCGACGTCTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGTACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAGCCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAGTTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAACTCGATGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAGATGGAAGGCGTCGA
CCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523