Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WCU19_RS10175 Genome accession   NZ_CP147611
Coordinates   2145981..2146637 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GN06758     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2140981..2151637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WCU19_RS10145 (WCU19_10145) dcyD 2141860..2142846 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  WCU19_RS10150 (WCU19_10150) tcyL 2142861..2143529 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WCU19_RS10155 (WCU19_10155) tcyN 2143526..2144278 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WCU19_RS10160 (WCU19_10160) sdiA 2144508..2145230 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  WCU19_RS10165 (WCU19_10165) yecF 2145298..2145522 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WCU19_RS10170 (WCU19_10170) yecU 2145509..2145685 (-) 177 WP_001307856.1 protein YecU -
  WCU19_RS10175 (WCU19_10175) letA 2145981..2146637 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WCU19_RS10180 (WCU19_10180) uvrC 2146634..2148466 (+) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  WCU19_RS10185 (WCU19_10185) pgsA 2148523..2149071 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WCU19_RS10205 (WCU19_10205) yecA 2149721..2150386 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=861778 WCU19_RS10175 WP_000611328.1 2145981..2146637(+) (letA) [Escherichia coli strain GN06758]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=861778 WCU19_RS10175 WP_000611328.1 2145981..2146637(+) (letA) [Escherichia coli strain GN06758]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482