Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   Q6378_RS10600 Genome accession   NZ_CP130889
Coordinates   2032077..2032472 (+) Length   131 a.a.
NCBI ID   WP_003703428.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NJ209649     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2025578..2036962 2032077..2032472 within 0


Gene organization within MGE regions


Location: 2025578..2036962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q6378_RS10565 (Q6378_10565) - 2025578..2026231 (+) 654 Protein_2037 TIGR01621 family pseudouridine synthase -
  Q6378_RS10595 (Q6378_10595) - 2031856..2031975 (+) 120 Protein_2038 competence protein ComE -
  Q6378_RS10600 (Q6378_10600) comE 2032077..2032472 (+) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  Q6378_RS10605 (Q6378_10605) comP 2032560..2033009 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  Q6378_RS10610 (Q6378_10610) - 2033386..2033532 (-) 147 WP_003691757.1 hypothetical protein -
  Q6378_RS10615 (Q6378_10615) - 2033919..2034509 (+) 591 WP_080229150.1 DNA cytosine methyltransferase -
  Q6378_RS10620 (Q6378_10620) - 2034548..2034877 (+) 330 WP_002234365.1 DNA cytosine methyltransferase -
  Q6378_RS10625 (Q6378_10625) - 2034891..2035748 (+) 858 WP_012503917.1 ATP-binding protein -
  Q6378_RS10630 (Q6378_10630) - 2035938..2036534 (+) 597 WP_012503916.1 TIGR02391 family protein -
  Q6378_RS10635 (Q6378_10635) - 2036540..2036962 (+) 423 WP_003691751.1 very short patch repair endonuclease -

Sequence

Protein


Download         Length: 131 a.a.        Molecular weight: 13796.61 Da        Isoelectric Point: 10.8790

>NTDB_id=861619 Q6378_RS10600 WP_003703428.1 2032077..2032472(+) (comE) [Neisseria gonorrhoeae strain NJ209649]
MSRGGATPYRFLLIRHIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAEY
RAQNGAFKSVDDLIKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK

Nucleotide


Download         Length: 396 bp        

>NTDB_id=861619 Q6378_RS10600 WP_003703428.1 2032077..2032472(+) (comE) [Neisseria gonorrhoeae strain NJ209649]
TTGAGCCGGGGCGGGGCAACGCCGTACCGGTTTTTGTTAATCCGCCATATCGTCGCAAGATGCGGTTTGTTGTTTGCAAC
CCTTAAAGGAAAAACCATGAAAAAAATGTTTGTATTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAA
ACATCAATGCGGCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATAC
CGCGCGCAAAACGGCGCGTTCAAGTCTGTGGACGATTTGATCAAGGTGAAGGGCATCGGTCCGGCGGTGCTGGCGAAGCT
GAAAGACCAGGCTTCCGTCGGCGCGCCCGCACCAAAAGGCCCCGCCAAACCGGTGCTGCCTGCGGTTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-110)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1