Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WCU49_RS10980 Genome accession   NZ_CP147555
Coordinates   2120331..2120987 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GN05064     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2115331..2125987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WCU49_RS10950 (WCU49_10950) dcyD 2116210..2117196 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  WCU49_RS10955 (WCU49_10955) tcyL 2117211..2117879 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WCU49_RS10960 (WCU49_10960) tcyN 2117876..2118628 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WCU49_RS10965 (WCU49_10965) sdiA 2118858..2119580 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  WCU49_RS10970 (WCU49_10970) yecF 2119648..2119872 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WCU49_RS10975 (WCU49_10975) yecU 2119859..2120035 (-) 177 WP_001307856.1 protein YecU -
  WCU49_RS10980 (WCU49_10980) letA 2120331..2120987 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WCU49_RS10985 (WCU49_10985) uvrC 2120984..2122816 (+) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  WCU49_RS10990 (WCU49_10990) pgsA 2122873..2123421 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WCU49_RS11010 (WCU49_11010) yecA 2124070..2124735 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=860423 WCU49_RS10980 WP_000611328.1 2120331..2120987(+) (letA) [Escherichia coli strain GN05064]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=860423 WCU49_RS10980 WP_000611328.1 2120331..2120987(+) (letA) [Escherichia coli strain GN05064]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482