Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   Q3V86_RS02445 Genome accession   NZ_CP130547
Coordinates   522658..523227 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain SA04-SX     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 517658..528227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3V86_RS02420 cysE 518870..519517 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  Q3V86_RS02425 cysS 519501..520901 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  Q3V86_RS02430 - 520894..521298 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  Q3V86_RS02435 rlmB 521306..522052 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  Q3V86_RS02440 - 522052..522576 (+) 525 WP_000664738.1 NYN domain-containing protein -
  Q3V86_RS02445 sigH 522658..523227 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  Q3V86_RS02450 rpmG 523342..523485 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  Q3V86_RS02455 secE 523541..523723 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  Q3V86_RS02460 nusG 523736..524284 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  Q3V86_RS02465 rplK 524465..524887 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  Q3V86_RS02470 rplA 525095..525787 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  Q3V86_RS02475 rplJ 526059..526559 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  Q3V86_RS02480 rplL 526602..526970 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  Q3V86_RS02485 - 527145..527753 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=860163 Q3V86_RS02445 WP_000872879.1 522658..523227(+) (sigH) [Staphylococcus aureus strain SA04-SX]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=860163 Q3V86_RS02445 WP_000872879.1 522658..523227(+) (sigH) [Staphylococcus aureus strain SA04-SX]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979