Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WCU03_RS13595 Genome accession   NZ_CP147535
Coordinates   2860909..2862741 (-) Length   610 a.a.
NCBI ID   WP_001283415.1    Uniprot ID   B1LQU4
Organism   Escherichia coli strain GN03551     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2855909..2867741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WCU03_RS13550 (WCU03_13550) yecR 2856256..2856579 (+) 324 WP_001237860.1 YecR-like lipofamily protein -
  WCU03_RS13555 (WCU03_13555) ftnA 2856751..2857248 (+) 498 WP_012311886.1 non-heme ferritin -
  WCU03_RS13560 (WCU03_13560) yecH 2857286..2857525 (-) 240 WP_000377223.1 YecH family metal-binding protein -
  WCU03_RS13565 (WCU03_13565) tyrP 2857716..2858927 (+) 1212 WP_000797560.1 tyrosine transporter TyrP -
  WCU03_RS13570 (WCU03_13570) yecA 2858989..2859654 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  WCU03_RS13590 (WCU03_13590) pgsA 2860304..2860852 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WCU03_RS13595 (WCU03_13595) uvrC 2860909..2862741 (-) 1833 WP_001283415.1 excinuclease ABC subunit UvrC Machinery gene
  WCU03_RS13600 (WCU03_13600) uvrY 2862738..2863250 (-) 513 Protein_2669 UvrY/SirA/GacA family response regulator transcription factor -
  WCU03_RS13605 (WCU03_13605) - 2863306..2864003 (+) 698 WP_250696820.1 IS1-like element IS1A family transposase -
  WCU03_RS13610 (WCU03_13610) - 2864019..2864171 (-) 153 Protein_2671 response regulator -
  WCU03_RS13615 (WCU03_13615) - 2864313..2864384 (+) 72 Protein_2672 transcriptional regulator -
  WCU03_RS13620 (WCU03_13620) yecU 2864467..2864643 (+) 177 WP_000590347.1 protein YecU -
  WCU03_RS13625 (WCU03_13625) yecF 2864630..2864854 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WCU03_RS13630 (WCU03_13630) sdiA 2864921..2865643 (-) 723 WP_001154279.1 transcriptional regulator SdiA -
  WCU03_RS13635 (WCU03_13635) tcyN 2865873..2866625 (-) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WCU03_RS13640 (WCU03_13640) tcyL 2866622..2867290 (-) 669 WP_001158220.1 cystine ABC transporter permease -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68243.11 Da        Isoelectric Point: 9.4502

>NTDB_id=860056 WCU03_RS13595 WP_001283415.1 2860909..2862741(-) (uvrC) [Escherichia coli strain GN03551]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGIRPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=860056 WCU03_RS13595 WP_001283415.1 2860909..2862741(-) (uvrC) [Escherichia coli strain GN03551]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCAAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGACGTTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCAGGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCTGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1LQU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374