Detailed information NTG0859638

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V75_RS09510
• Genome accession: NZ_CP130529
• Coordinates: 1942076..1943119 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA17-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1937076..1948119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V75_RS09480	-	1937497..1938753 (-)	1257	WP_075583716.1	aminopeptidase	-
Q3V75_RS09485	-	1938756..1938956 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V75_RS09490	-	1939103..1939567 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V75_RS09495	-	1939574..1939849 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V75_RS09500	-	1940127..1941344 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V75_RS09505	vraR	1941457..1942086 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V75_RS09510	vraS	1942076..1943119 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V75_RS09515	liaF	1943116..1943817 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V75_RS09520	-	1943832..1944218 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V75_RS09525	map	1944435..1945193 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V75_RS09530	-	1945722..1946708 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V75_RS09535	-	1947139..1947552 (-)	414	WP_001670387.1	hypothetical protein	-
Q3V75_RS09540	-	1947581..1947691 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859638 Q3V75_RS09510 WP_001017131.1 1942076..1943119(-) (vraS) [Staphylococcus aureus strain SA17-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859638 Q3V75_RS09510 WP_001017131.1 1942076..1943119(-) (vraS) [Staphylococcus aureus strain SA17-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1