Detailed information NTG0859425

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V73_RS09925
• Genome accession: NZ_CP130523
• Coordinates: 2005094..2006137 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA22-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2000094..2011137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V73_RS09895	-	2000516..2001772 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V73_RS09900	-	2001775..2001975 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V73_RS09905	-	2002122..2002586 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V73_RS09910	-	2002593..2002868 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V73_RS09915	-	2003146..2004390 (+)	1245	WP_064125696.1	YihY/virulence factor BrkB family protein	-
Q3V73_RS09920	vraR	2004475..2005104 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V73_RS09925	vraS	2005094..2006137 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V73_RS09930	liaF	2006134..2006835 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V73_RS09935	-	2006850..2007236 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V73_RS09940	map	2007453..2008211 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V73_RS09945	-	2008740..2009726 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V73_RS09950	-	2010159..2010572 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V73_RS09955	-	2010601..2010711 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859425 Q3V73_RS09925 WP_001017131.1 2005094..2006137(-) (vraS) [Staphylococcus aureus strain SA22-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859425 Q3V73_RS09925 WP_001017131.1 2005094..2006137(-) (vraS) [Staphylococcus aureus strain SA22-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1