Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WAZ92_RS09035 Genome accession   NZ_CP147101
Coordinates   1871928..1872584 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain KFu021     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1866928..1877584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAZ92_RS09000 (WAZ92_09000) dcyD 1867808..1868794 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WAZ92_RS09005 (WAZ92_09005) tcyL 1868809..1869477 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WAZ92_RS09010 (WAZ92_09010) tcyN 1869474..1870226 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WAZ92_RS09015 (WAZ92_09015) sdiA 1870456..1871178 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  WAZ92_RS09020 (WAZ92_09020) yecF 1871245..1871469 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WAZ92_RS09025 (WAZ92_09025) yecU 1871456..1871632 (-) 177 WP_000590344.1 protein YecU -
  WAZ92_RS09030 (WAZ92_09030) - 1871670..1871786 (-) 117 WP_001302039.1 hypothetical protein -
  WAZ92_RS09035 (WAZ92_09035) letA 1871928..1872584 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WAZ92_RS09040 (WAZ92_09040) uvrC 1872581..1874413 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WAZ92_RS09045 (WAZ92_09045) pgsA 1874470..1875018 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WAZ92_RS09065 (WAZ92_09065) yecA 1875668..1876333 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=858891 WAZ92_RS09035 WP_000611328.1 1871928..1872584(+) (letA) [Escherichia coli strain KFu021]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=858891 WAZ92_RS09035 WP_000611328.1 1871928..1872584(+) (letA) [Escherichia coli strain KFu021]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482