Detailed information NTG0858817

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V77_RS10010
• Genome accession: NZ_CP130503
• Coordinates: 2015097..2016140 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA36-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2010097..2021140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V77_RS09980	-	2010518..2011774 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V77_RS09985	-	2011777..2011977 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V77_RS09990	-	2012124..2012588 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V77_RS09995	-	2012595..2012870 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V77_RS10000	-	2013148..2014365 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V77_RS10005	vraR	2014478..2015107 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V77_RS10010	vraS	2015097..2016140 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V77_RS10015	liaF	2016137..2016838 (-)	702	WP_303050047.1	cell wall-active antibiotics response protein LiaF	-
Q3V77_RS10020	-	2016853..2017239 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V77_RS10025	map	2017456..2018214 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V77_RS10030	-	2018743..2019729 (+)	987	WP_155560248.1	aromatic acid exporter family protein	-
Q3V77_RS10035	-	2020161..2020574 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V77_RS10040	-	2020603..2020713 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=858817 Q3V77_RS10010 WP_001017131.1 2015097..2016140(-) (vraS) [Staphylococcus aureus strain SA36-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=858817 Q3V77_RS10010 WP_001017131.1 2015097..2016140(-) (vraS) [Staphylococcus aureus strain SA36-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1