Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WAZ86_RS12650 Genome accession   NZ_CP147084
Coordinates   2554513..2555169 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain KTa005     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2549513..2560169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAZ86_RS12620 (WAZ86_12620) - 2550643..2551383 (+) 741 WP_032176377.1 hypothetical protein -
  WAZ86_RS12640 (WAZ86_12640) pgsA 2552079..2552627 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WAZ86_RS12645 (WAZ86_12645) uvrC 2552684..2554516 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WAZ86_RS12650 (WAZ86_12650) letA 2554513..2555169 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WAZ86_RS12655 (WAZ86_12655) - 2555311..2555382 (+) 72 Protein_2469 transcriptional regulator -
  WAZ86_RS12660 (WAZ86_12660) yecU 2555465..2555641 (+) 177 WP_000590347.1 protein YecU -
  WAZ86_RS12665 (WAZ86_12665) yecF 2555628..2555852 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WAZ86_RS12670 (WAZ86_12670) sdiA 2555919..2556641 (-) 723 WP_077477607.1 transcriptional regulator SdiA -
  WAZ86_RS12675 (WAZ86_12675) tcyN 2556871..2557623 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WAZ86_RS12680 (WAZ86_12680) tcyL 2557620..2558288 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WAZ86_RS12685 (WAZ86_12685) dcyD 2558303..2559289 (-) 987 WP_325912827.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=858733 WAZ86_RS12650 WP_000611335.1 2554513..2555169(-) (letA) [Escherichia coli strain KTa005]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=858733 WAZ86_RS12650 WP_000611335.1 2554513..2555169(-) (letA) [Escherichia coli strain KTa005]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486