Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WAZ51_RS10365 Genome accession   NZ_CP147050
Coordinates   2124550..2125206 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 1008S19     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2119550..2130206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WAZ51_RS10325 (WAZ51_10325) dcyD 2119652..2120638 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WAZ51_RS10330 (WAZ51_10330) tcyL 2120653..2121321 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WAZ51_RS10335 (WAZ51_10335) tcyN 2121318..2122070 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WAZ51_RS10340 (WAZ51_10340) - 2122289..2122986 (+) 698 WP_103215986.1 IS1-like element IS1A family transposase -
  WAZ51_RS10345 (WAZ51_10345) sdiA 2123077..2123799 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  WAZ51_RS10350 (WAZ51_10350) yecF 2123867..2124091 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WAZ51_RS10355 (WAZ51_10355) yecU 2124078..2124254 (-) 177 WP_000590344.1 protein YecU -
  WAZ51_RS10360 (WAZ51_10360) - 2124292..2124408 (-) 117 WP_001302039.1 hypothetical protein -
  WAZ51_RS10365 (WAZ51_10365) letA 2124550..2125206 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WAZ51_RS10370 (WAZ51_10370) uvrC 2125203..2127035 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  WAZ51_RS10375 (WAZ51_10375) pgsA 2127092..2127640 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WAZ51_RS10395 (WAZ51_10395) - 2128335..2128979 (-) 645 Protein_2015 hypothetical protein -
  WAZ51_RS10400 (WAZ51_10400) - 2129034..2129731 (+) 698 WP_103215986.1 IS1-like element IS1A family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=858082 WAZ51_RS10365 WP_000611328.1 2124550..2125206(+) (letA) [Escherichia coli strain 1008S19]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=858082 WAZ51_RS10365 WP_000611328.1 2124550..2125206(+) (letA) [Escherichia coli strain 1008S19]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482