Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V8N89_RS17050 Genome accession   NZ_CP147009
Coordinates   3433749..3434405 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FACU 2024     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3428749..3439405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8N89_RS17020 yecA 3430000..3430665 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  V8N89_RS17040 pgsA 3431315..3431863 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V8N89_RS17045 uvrC 3431920..3433752 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  V8N89_RS17050 letA 3433749..3434405 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V8N89_RS17055 - 3434547..3434618 (+) 72 Protein_3324 transcriptional regulator -
  V8N89_RS17060 yecU 3434701..3434877 (+) 177 WP_001307856.1 protein YecU -
  V8N89_RS17065 yecF 3434864..3435088 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  V8N89_RS17070 sdiA 3435155..3435877 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  V8N89_RS17075 tcyN 3436107..3436859 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V8N89_RS17080 tcyL 3436856..3437524 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  V8N89_RS17085 dcyD 3437539..3438525 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=857532 V8N89_RS17050 WP_000611328.1 3433749..3434405(-) (letA) [Escherichia coli strain FACU 2024]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=857532 V8N89_RS17050 WP_000611328.1 3433749..3434405(-) (letA) [Escherichia coli strain FACU 2024]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482