Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WA132_RS19660 Genome accession   NZ_CP146939
Coordinates   4088202..4090034 (+) Length   610 a.a.
NCBI ID   WP_001283421.1    Uniprot ID   P0A8G1
Organism   Escherichia coli strain 2A     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4083202..4095034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WA132_RS19625 (WA132_19625) dcyD 4083428..4084414 (+) 987 WP_001764596.1 D-cysteine desulfhydrase -
  WA132_RS19630 (WA132_19630) tcyL 4084429..4085097 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WA132_RS19635 (WA132_19635) tcyN 4085094..4085846 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WA132_RS19640 (WA132_19640) sdiA 4086076..4086798 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  WA132_RS19645 (WA132_19645) yecF 4086866..4087090 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WA132_RS19650 (WA132_19650) yecU 4087077..4087253 (-) 177 WP_001307856.1 protein YecU -
  WA132_RS19655 (WA132_19655) letA 4087549..4088205 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WA132_RS19660 (WA132_19660) uvrC 4088202..4090034 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WA132_RS19665 (WA132_19665) pgsA 4090091..4090639 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WA132_RS19685 (WA132_19685) yecA 4091288..4091953 (+) 666 WP_000847882.1 UPF0149 family protein YecA -
  WA132_RS19690 (WA132_19690) tyrP 4092015..4093226 (-) 1212 WP_000797555.1 tyrosine transporter TyrP -
  WA132_RS19695 (WA132_19695) yecH 4093417..4093656 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  WA132_RS19700 (WA132_19700) ftnA 4093694..4094191 (-) 498 WP_000917208.1 non-heme ferritin -
  WA132_RS19705 (WA132_19705) yecR 4094363..4094686 (-) 324 WP_001237881.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68188.03 Da        Isoelectric Point: 9.3685

>NTDB_id=857400 WA132_RS19660 WP_001283421.1 4088202..4090034(+) (uvrC) [Escherichia coli strain 2A]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=857400 WA132_RS19660 WP_001283421.1 4088202..4090034(+) (uvrC) [Escherichia coli strain 2A]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTACTG
GAACACAACTACATCAAACTTTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGAGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AACCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCGCGGATTCGCGACCAAATTCAGGCGGTGCGACGTGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGAGTGGCGTTCGATGCGGGTATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGTGGCGATAGAGCGCGTTATCTGAAACTCGCGCGTACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTACGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCTA
TCGACGACAGTAAGATCCCGGATGTGATCCTTATTGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTTTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGTGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0A8G1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374