Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V9Z43_RS10955 Genome accession   NZ_CP146687
Coordinates   2239683..2240339 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MS 198-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2234683..2245339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z43_RS10925 (V9Z43_10925) dcyD 2235562..2236548 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  V9Z43_RS10930 (V9Z43_10930) tcyL 2236563..2237231 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  V9Z43_RS10935 (V9Z43_10935) tcyN 2237228..2237980 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V9Z43_RS10940 (V9Z43_10940) sdiA 2238210..2238932 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  V9Z43_RS10945 (V9Z43_10945) yecF 2239000..2239224 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  V9Z43_RS10950 (V9Z43_10950) yecU 2239211..2239387 (-) 177 WP_000590347.1 protein YecU -
  V9Z43_RS10955 (V9Z43_10955) letA 2239683..2240339 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V9Z43_RS10960 (V9Z43_10960) uvrC 2240336..2242168 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  V9Z43_RS10965 (V9Z43_10965) pgsA 2242225..2242773 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V9Z43_RS10985 (V9Z43_10985) yecA 2243423..2244088 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=857056 V9Z43_RS10955 WP_000611328.1 2239683..2240339(+) (letA) [Escherichia coli strain MS 198-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=857056 V9Z43_RS10955 WP_000611328.1 2239683..2240339(+) (letA) [Escherichia coli strain MS 198-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482