Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V9Z38_RS10175 Genome accession   NZ_CP146675
Coordinates   2153085..2153741 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MS 69-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2148085..2158741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z38_RS10145 (V9Z38_10145) dcyD 2148964..2149950 (+) 987 WP_001128229.1 D-cysteine desulfhydrase -
  V9Z38_RS10150 (V9Z38_10150) tcyL 2149965..2150633 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  V9Z38_RS10155 (V9Z38_10155) tcyN 2150630..2151382 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V9Z38_RS10160 (V9Z38_10160) sdiA 2151612..2152334 (+) 723 WP_001154274.1 transcriptional regulator SdiA -
  V9Z38_RS10165 (V9Z38_10165) yecF 2152402..2152626 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  V9Z38_RS10170 (V9Z38_10170) yecU 2152613..2152789 (-) 177 WP_000590347.1 protein YecU -
  V9Z38_RS10175 (V9Z38_10175) letA 2153085..2153741 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V9Z38_RS10180 (V9Z38_10180) uvrC 2153738..2155570 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  V9Z38_RS10185 (V9Z38_10185) pgsA 2155627..2156175 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V9Z38_RS10205 (V9Z38_10205) yecA 2156825..2157490 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=856798 V9Z38_RS10175 WP_000611328.1 2153085..2153741(+) (letA) [Escherichia coli strain MS 69-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=856798 V9Z38_RS10175 WP_000611328.1 2153085..2153741(+) (letA) [Escherichia coli strain MS 69-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482