Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V9Z46_RS09515 Genome accession   NZ_CP146665
Coordinates   1957149..1957805 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MS 115-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1952149..1962805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z46_RS09480 (V9Z46_09480) dcyD 1953029..1954015 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  V9Z46_RS09485 (V9Z46_09485) tcyL 1954030..1954698 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  V9Z46_RS09490 (V9Z46_09490) tcyN 1954695..1955447 (+) 753 WP_001273002.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V9Z46_RS09495 (V9Z46_09495) sdiA 1955677..1956399 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  V9Z46_RS09500 (V9Z46_09500) yecF 1956466..1956690 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  V9Z46_RS09505 (V9Z46_09505) yecU 1956677..1956853 (-) 177 WP_000590347.1 protein YecU -
  V9Z46_RS09510 (V9Z46_09510) - 1956936..1957007 (-) 72 Protein_1855 transcriptional regulator -
  V9Z46_RS09515 (V9Z46_09515) letA 1957149..1957805 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V9Z46_RS09520 (V9Z46_09520) uvrC 1957802..1959634 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  V9Z46_RS09525 (V9Z46_09525) pgsA 1959691..1960239 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V9Z46_RS09545 (V9Z46_09545) yecA 1960889..1961554 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=856547 V9Z46_RS09515 WP_000611335.1 1957149..1957805(+) (letA) [Escherichia coli strain MS 115-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=856547 V9Z46_RS09515 WP_000611335.1 1957149..1957805(+) (letA) [Escherichia coli strain MS 115-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486