Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V8690_RS23770 Genome accession   NZ_CP146350
Coordinates   5087831..5088514 (+) Length   227 a.a.
NCBI ID   WP_338781883.1    Uniprot ID   -
Organism   Streptomyces sp. DG1A-41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5082831..5093514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8690_RS23750 (V8690_23750) - 5083088..5083954 (+) 867 WP_338781876.1 alpha/beta hydrolase -
  V8690_RS23755 (V8690_23755) - 5084218..5085219 (+) 1002 WP_338781878.1 alpha/beta hydrolase -
  V8690_RS23760 (V8690_23760) - 5085212..5086453 (+) 1242 WP_338781880.1 acyltransferase -
  V8690_RS23765 (V8690_23765) - 5086446..5087834 (+) 1389 WP_338781881.1 sensor histidine kinase -
  V8690_RS23770 (V8690_23770) vraR 5087831..5088514 (+) 684 WP_338781883.1 response regulator transcription factor Regulator
  V8690_RS23775 (V8690_23775) - 5088632..5089969 (+) 1338 WP_338781885.1 histidine kinase -
  V8690_RS23780 (V8690_23780) vraR 5089966..5090631 (+) 666 WP_338781888.1 response regulator transcription factor Regulator
  V8690_RS23785 (V8690_23785) - 5090817..5091473 (+) 657 Protein_4681 DUF1326 domain-containing protein -
  V8690_RS23790 (V8690_23790) - 5091591..5092214 (+) 624 WP_338785435.1 DUF1326 domain-containing protein -
  V8690_RS23795 (V8690_23795) - 5092263..5093099 (-) 837 WP_338781890.1 DUF2182 domain-containing protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24258.91 Da        Isoelectric Point: 4.7513

>NTDB_id=855152 V8690_RS23770 WP_338781883.1 5087831..5088514(+) (vraR) [Streptomyces sp. DG1A-41]
MTSSSGRPIRVLIVDDQAMVRQGFTVLLGTQPDIEVVGEAKDGEGGIAKAAETAPDVVLMDIRMPGIGGIEATERITTAT
PDIKVLVLTTFDLDEYVYDALRAGASGFLLKDASSEQLAEAVRVIAAGDALLAPGITRKLIAEFSRLDGRPRAPLKERIG
DLTERETEVLALIAQGLSNAEISKLLFVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSGY

Nucleotide


Download         Length: 684 bp        

>NTDB_id=855152 V8690_RS23770 WP_338781883.1 5087831..5088514(+) (vraR) [Streptomyces sp. DG1A-41]
ATGACGAGCAGCTCCGGCCGACCCATCCGGGTCCTCATCGTCGACGACCAGGCGATGGTCCGGCAGGGTTTCACCGTGCT
GCTCGGCACCCAGCCCGACATAGAGGTCGTCGGCGAGGCGAAGGACGGGGAGGGCGGCATCGCGAAGGCCGCCGAGACCG
CCCCGGACGTCGTCCTCATGGACATCCGGATGCCCGGCATCGGCGGCATCGAGGCCACCGAGCGCATCACCACCGCGACC
CCGGACATCAAGGTGCTGGTGCTCACCACCTTCGACCTCGACGAGTACGTGTACGACGCGCTGCGCGCCGGAGCCTCCGG
GTTCCTGCTGAAGGACGCGTCGTCGGAGCAGCTCGCCGAGGCGGTCCGGGTGATCGCGGCCGGCGACGCGCTGCTCGCCC
CGGGCATCACCCGCAAGTTGATCGCCGAGTTCTCCCGGCTGGACGGCCGACCCCGCGCCCCGCTCAAGGAGCGGATCGGT
GACTTGACCGAGCGGGAGACGGAGGTGCTCGCCCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCTCCAAGCTGCTGTT
CGTCGCCGAGCAGACGGTGAAGACCCATGTGGGCCGGATCCTGGTGAAGCTGGGCCTGAGGGACCGGACGCAGGCGGCGG
TGTTCGCGTACGAGTCGGGGCTGGTCCGGCCGTCGGGGTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-123)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.047

94.714

0.436
  degU Bacillus subtilis subsp. subtilis str. 168

39.91

98.238

0.392