Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V1460_RS24235 Genome accession   NZ_CP146101
Coordinates   5417626..5418270 (-) Length   214 a.a.
NCBI ID   WP_338675720.1    Uniprot ID   -
Organism   Streptomyces sp. SCSIO 30461     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5412626..5423270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V1460_RS24205 (V1460_24205) - 5412966..5413736 (-) 771 WP_338675714.1 sulfite exporter TauE/SafE family protein -
  V1460_RS24210 (V1460_24210) - 5413822..5414790 (-) 969 WP_338675715.1 SPFH domain-containing protein -
  V1460_RS24215 (V1460_24215) - 5414893..5415321 (-) 429 WP_338675716.1 NfeD family protein -
  V1460_RS24220 (V1460_24220) - 5415402..5416196 (-) 795 WP_338675717.1 ABC transporter ATP-binding protein -
  V1460_RS24225 (V1460_24225) - 5416330..5417127 (+) 798 WP_338675718.1 hypothetical protein -
  V1460_RS24230 (V1460_24230) - 5417211..5417453 (-) 243 WP_338675719.1 chaplin family protein -
  V1460_RS24235 (V1460_24235) vraR 5417626..5418270 (-) 645 WP_338675720.1 response regulator transcription factor Regulator
  V1460_RS24240 (V1460_24240) - 5418263..5419420 (-) 1158 WP_338675721.1 GAF domain-containing sensor histidine kinase -
  V1460_RS24245 (V1460_24245) - 5419589..5420302 (+) 714 WP_338675722.1 SDR family NAD(P)-dependent oxidoreductase -
  V1460_RS24250 (V1460_24250) - 5420308..5421435 (+) 1128 WP_338675723.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  V1460_RS24255 (V1460_24255) - 5421713..5422447 (+) 735 WP_338675724.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23243.63 Da        Isoelectric Point: 4.8725

>NTDB_id=854657 V1460_RS24235 WP_338675720.1 5417626..5418270(-) (vraR) [Streptomyces sp. SCSIO 30461]
MGDKGIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVEQAQELCPDVVLMDVKMPGMDGIEALRRLRALDNPV
KVLVVTSFMERRTVIPALRAGASGYVYKDIDPDALAGAVRSVYAGHVLLQPEVADVLLSEDEPGTGQGRGTSLTEREREV
LALIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLSS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=854657 V1460_RS24235 WP_338675720.1 5417626..5418270(-) (vraR) [Streptomyces sp. SCSIO 30461]
GTGGGTGACAAGGGAATCCGCGTGCTGCTCGTGGACGATCACCAGGTCGTCCGCCGGGGTCTGCGCACCTTCCTCGAGGT
GCAGGACGACATCGAGGTGGTGGGGGAGGCCGCCGACGGCGCCGAGGGTGTGGAGCAGGCCCAGGAACTGTGCCCTGACG
TCGTGCTGATGGACGTGAAGATGCCGGGCATGGACGGGATCGAGGCCCTGCGCCGGCTGCGCGCCCTGGACAACCCGGTG
AAGGTGCTGGTGGTCACGAGCTTCATGGAGCGGCGCACCGTGATCCCGGCGCTTCGCGCGGGTGCCTCCGGCTATGTGTA
CAAGGACATCGATCCGGATGCCCTGGCCGGTGCCGTCCGCTCCGTGTACGCGGGGCATGTACTGCTCCAGCCCGAGGTGG
CCGACGTGCTGCTCTCGGAGGACGAGCCAGGCACGGGGCAGGGGAGGGGCACCTCGCTCACCGAGCGGGAGCGCGAGGTG
CTCGCGCTGATCGCCGACGGTCGCTCCAACCGCGAGATAGCACGCGCGCTGGTCCTCTCGGAGAAGACGGTGAAGACCCA
TGTGTCGAACATTCTGATGAAGCTGGATCTGGCAGACCGTACACAGGCGGCGCTCTGGGCCGTACGCCATGGACTCAGCA
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.377

96.729

0.449
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.397