Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V1460_RS09135 Genome accession   NZ_CP146101
Coordinates   2006050..2006763 (-) Length   237 a.a.
NCBI ID   WP_338673230.1    Uniprot ID   -
Organism   Streptomyces sp. SCSIO 30461     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2001050..2011763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V1460_RS09110 (V1460_09110) - 2001730..2003169 (+) 1440 WP_338673225.1 gamma-aminobutyraldehyde dehydrogenase -
  V1460_RS09115 (V1460_09115) - 2003311..2003868 (-) 558 WP_338673226.1 TetR/AcrR family transcriptional regulator -
  V1460_RS09120 (V1460_09120) - 2003865..2004227 (-) 363 WP_338673227.1 DUF1304 domain-containing protein -
  V1460_RS09125 (V1460_09125) - 2004433..2004699 (+) 267 Protein_1789 hypothetical protein -
  V1460_RS09130 (V1460_09130) - 2004760..2005953 (-) 1194 WP_338673229.1 serine hydrolase domain-containing protein -
  V1460_RS09135 (V1460_09135) vraR 2006050..2006763 (-) 714 WP_338673230.1 response regulator transcription factor Regulator
  V1460_RS09140 (V1460_09140) - 2006760..2007887 (-) 1128 WP_407077599.1 sensor histidine kinase -
  V1460_RS09145 (V1460_09145) - 2007982..2008669 (-) 688 Protein_1793 glycerophosphodiester phosphodiesterase -
  V1460_RS09150 (V1460_09150) - 2008680..2009705 (-) 1026 WP_338673232.1 adenosine deaminase -
  V1460_RS09155 (V1460_09155) - 2009819..2010601 (+) 783 WP_338673233.1 DUF4190 domain-containing protein -
  V1460_RS09160 (V1460_09160) - 2010715..2011311 (-) 597 WP_338673234.1 NADAR family protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 25238.89 Da        Isoelectric Point: 5.8909

>NTDB_id=854641 V1460_RS09135 WP_338673230.1 2006050..2006763(-) (vraR) [Streptomyces sp. SCSIO 30461]
MTIRVVVADDQELVRSGLVMILEAQQDIEVVAEAEDGVAAVDAVRRHSPDVALLDVRMPGADGIEACRTISALSTCRTVM
LTTFDTDEYVFEALQAGASGFLLKDVRRDDLVHAVRVAARGDSLLAPSVARRLVEEFTQRAARPRAALDCGRLDALTARE
RETLLLLGHGLSNAEIAARLVVSEHTVKTHVGNVLSKLGLRDRVQAVICAYETGLIAAGHPPHGGAGLAASPVPARN

Nucleotide


Download         Length: 714 bp        

>NTDB_id=854641 V1460_RS09135 WP_338673230.1 2006050..2006763(-) (vraR) [Streptomyces sp. SCSIO 30461]
TTGACGATCCGTGTGGTGGTGGCCGATGACCAGGAGTTGGTGCGCAGCGGCCTCGTGATGATCCTGGAGGCCCAGCAGGA
CATCGAGGTCGTGGCCGAGGCCGAGGACGGGGTGGCAGCCGTGGACGCGGTACGCCGCCACTCCCCTGATGTGGCACTGC
TCGACGTCCGGATGCCCGGTGCGGACGGGATCGAGGCCTGCCGCACCATCAGCGCCCTATCCACCTGCCGCACCGTGATG
CTGACGACGTTCGACACCGACGAGTACGTCTTCGAGGCGCTGCAGGCGGGCGCCAGTGGCTTCCTGCTGAAGGACGTACG
CCGCGACGACCTCGTGCACGCGGTGCGGGTCGCGGCACGGGGCGACTCGCTTCTCGCGCCTTCGGTGGCCCGCCGGTTGG
TGGAGGAGTTCACCCAGCGCGCCGCACGTCCCCGGGCGGCGCTGGACTGCGGACGGCTGGACGCGCTGACGGCACGGGAA
CGGGAGACGCTGCTCCTGCTGGGGCACGGGCTGTCCAACGCGGAGATCGCGGCAAGACTCGTGGTCAGTGAGCACACCGT
CAAGACGCATGTGGGCAACGTGCTGTCGAAGCTCGGCCTGCGGGACCGTGTCCAGGCGGTCATCTGCGCCTACGAGACGG
GGTTGATCGCCGCAGGGCATCCCCCGCACGGGGGAGCAGGACTCGCTGCCTCCCCCGTACCGGCGAGGAACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.014

91.561

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

94.093

0.371