Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V2W30_RS12460 Genome accession   NZ_CP146022
Coordinates   2664290..2664967 (+) Length   225 a.a.
NCBI ID   WP_338696138.1    Uniprot ID   A0ACD5AA36
Organism   Streptomyces sp. Q6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2659290..2669967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2W30_RS12440 (V2W30_12440) - 2659798..2660448 (+) 651 WP_338696135.1 TetR family transcriptional regulator -
  V2W30_RS12445 (V2W30_12445) - 2660623..2661834 (+) 1212 WP_338696136.1 alpha/beta hydrolase -
  V2W30_RS12450 (V2W30_12450) - 2661911..2662786 (+) 876 WP_338696137.1 DUF4429 domain-containing protein -
  V2W30_RS12455 (V2W30_12455) - 2663031..2664275 (+) 1245 WP_338703579.1 sensor histidine kinase -
  V2W30_RS12460 (V2W30_12460) vraR 2664290..2664967 (+) 678 WP_338696138.1 response regulator transcription factor Regulator
  V2W30_RS12465 (V2W30_12465) - 2665169..2666299 (+) 1131 WP_338696139.1 alpha/beta hydrolase -
  V2W30_RS12470 (V2W30_12470) - 2666296..2667525 (+) 1230 WP_338696140.1 acyltransferase -
  V2W30_RS12475 (V2W30_12475) - 2667628..2668572 (-) 945 WP_338703580.1 aldo/keto reductase -
  V2W30_RS12480 (V2W30_12480) - 2668683..2669150 (-) 468 WP_338696142.1 MerR family transcriptional regulator -
  V2W30_RS12485 (V2W30_12485) - 2669247..2669714 (+) 468 WP_338696144.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24159.01 Da        Isoelectric Point: 6.4979

>NTDB_id=854563 V2W30_RS12460 WP_338696138.1 2664290..2664967(+) (vraR) [Streptomyces sp. Q6]
MTIRVIIVDDQSMVRAGFAALLSAQSDIDVVGEAPDGKQGVEVSRSTHPDVVLMDVRMPEMDGLAATQELLNPPPGVSHR
PKVLMLTTFDVDDYVYAALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPTVTKRLIADFTQAQPVRRKEHSPKLKSL
TPRELEVLELIARGLSNQEIAQKLVLAEQTVKTHIGRVLAKIGLRDRAQAVIFAYESGLVTPGGQ

Nucleotide


Download         Length: 678 bp        

>NTDB_id=854563 V2W30_RS12460 WP_338696138.1 2664290..2664967(+) (vraR) [Streptomyces sp. Q6]
ATGACCATCCGCGTGATCATCGTCGACGACCAGAGCATGGTCCGGGCCGGCTTCGCAGCGCTGTTGTCCGCGCAGAGCGA
CATCGACGTCGTGGGCGAGGCCCCGGACGGCAAGCAGGGCGTCGAGGTGAGCCGGTCCACTCATCCGGACGTCGTCCTCA
TGGACGTGCGGATGCCGGAGATGGACGGGCTCGCCGCGACCCAGGAGTTGCTGAACCCGCCGCCGGGCGTATCGCACCGT
CCCAAGGTTCTGATGCTCACGACGTTCGACGTGGACGACTATGTGTACGCGGCCCTGCGGGCGGGCGCGTCCGGTTTCCT
GCTCAAGGACGCGCCGCCCGCCGATCTGATCGCCGCCGTGCGCGTGGTCGCGGCGGGTGAGGCACTGCTCGCGCCGACCG
TCACCAAGCGGCTCATCGCGGACTTCACACAGGCCCAGCCGGTGCGCCGCAAGGAGCACTCGCCGAAGTTGAAGAGCCTG
ACACCGCGTGAGCTCGAAGTGCTCGAGCTGATCGCGCGGGGACTGTCCAACCAGGAGATCGCGCAGAAGCTGGTCCTGGC
CGAACAGACGGTGAAGACCCACATCGGCCGCGTCCTGGCGAAGATCGGGCTGCGCGACCGCGCCCAGGCCGTGATCTTCG
CGTACGAGTCCGGGCTCGTCACCCCCGGCGGGCAGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.818

97.778

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

37.118

100

0.378