Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V2W30_RS05420 Genome accession   NZ_CP146022
Coordinates   1132794..1133444 (+) Length   216 a.a.
NCBI ID   WP_338694088.1    Uniprot ID   A0ACD5A758
Organism   Streptomyces sp. Q6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127794..1138444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2W30_RS05390 (V2W30_05390) mug 1127831..1128394 (+) 564 WP_338703493.1 G/U mismatch-specific DNA glycosylase -
  V2W30_RS05395 (V2W30_05395) - 1128391..1129197 (-) 807 WP_338694082.1 SAM-dependent methyltransferase -
  V2W30_RS05400 (V2W30_05400) - 1129326..1129745 (-) 420 WP_338694083.1 hypothetical protein -
  V2W30_RS05405 (V2W30_05405) - 1129790..1130530 (-) 741 WP_338694084.1 ABC transporter permease -
  V2W30_RS05410 (V2W30_05410) - 1130527..1131450 (-) 924 WP_338694085.1 ATP-binding cassette domain-containing protein -
  V2W30_RS05415 (V2W30_05415) - 1131559..1132779 (+) 1221 WP_338694086.1 histidine kinase -
  V2W30_RS05420 (V2W30_05420) vraR 1132794..1133444 (+) 651 WP_338694088.1 response regulator transcription factor Regulator
  V2W30_RS05425 (V2W30_05425) - 1133576..1134733 (+) 1158 WP_338694090.1 ROK family transcriptional regulator -
  V2W30_RS05430 (V2W30_05430) - 1134985..1135746 (-) 762 WP_338694091.1 GntR family transcriptional regulator -
  V2W30_RS05435 (V2W30_05435) sigJ 1136048..1136950 (-) 903 WP_338694092.1 RNA polymerase sigma factor SigJ -
  V2W30_RS05440 (V2W30_05440) - 1137128..1137958 (+) 831 WP_338694094.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22859.40 Da        Isoelectric Point: 4.8419

>NTDB_id=854550 V2W30_RS05420 WP_338694088.1 1132794..1133444(+) (vraR) [Streptomyces sp. Q6]
MPITVLLVDDEPLVRAGLRAVLEAQSDIEVVGEATDGAAVVPLVRELRPDVVAMDVRMPLLDGIEATRAVLRTVEGPPKI
LVITTFENDEYVYGALRAGADGFLLKRARPAEIVHAVRLVAAGESLLFPAAVRKLAAEYGNASARDALERAALTEREASV
LRLMARGLSNAEIAADLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPS

Nucleotide


Download         Length: 651 bp        

>NTDB_id=854550 V2W30_RS05420 WP_338694088.1 1132794..1133444(+) (vraR) [Streptomyces sp. Q6]
GTGCCGATCACCGTGCTCCTCGTCGACGACGAACCCCTCGTCCGCGCGGGGCTGCGCGCCGTACTGGAAGCGCAGTCCGA
CATCGAAGTGGTGGGCGAGGCCACCGACGGCGCGGCCGTCGTTCCGCTGGTGCGCGAACTGCGCCCCGACGTGGTCGCCA
TGGACGTACGGATGCCGCTGCTCGACGGGATCGAGGCCACGCGCGCGGTCCTGCGCACCGTGGAGGGGCCGCCGAAGATC
CTCGTGATCACGACGTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGGGCGGGCGCCGACGGGTTCCTCCTGAAGCG
GGCCAGGCCCGCCGAGATCGTGCACGCCGTCCGCCTCGTCGCGGCGGGCGAGTCCCTCCTCTTCCCGGCGGCGGTGCGGA
AACTGGCGGCCGAGTACGGCAACGCCTCCGCCCGGGACGCCCTGGAGCGGGCCGCGCTGACCGAGCGCGAGGCGTCGGTG
CTGCGGCTGATGGCGCGGGGCCTGTCGAACGCGGAGATCGCCGCGGATCTCGTCGTCGGCACCGAGACGGTCAAGTCCCA
TGTGAGCGCGGTGCTGGCCAAGCTCGGGGCCCGCGATCGAACCCAGGCGGTCATCGCCGCGTACGAATCCGGTTTCGTCG
CGCCGAGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-206)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.056

99.074

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

35.841

100

0.375