Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V2W30_RS03755 Genome accession   NZ_CP146022
Coordinates   774644..775309 (-) Length   221 a.a.
NCBI ID   WP_338693633.1    Uniprot ID   A0ACD5A9L6
Organism   Streptomyces sp. Q6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 769644..780309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2W30_RS03735 (V2W30_03735) - 770315..771499 (+) 1185 WP_338703467.1 MFS transporter -
  V2W30_RS03740 (V2W30_03740) - 771551..772294 (+) 744 WP_338693630.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  V2W30_RS03745 (V2W30_03745) - 772340..772771 (-) 432 WP_338693631.1 MarR family transcriptional regulator -
  V2W30_RS03750 (V2W30_03750) - 772859..774376 (+) 1518 WP_338693632.1 MFS transporter -
  V2W30_RS03755 (V2W30_03755) vraR 774644..775309 (-) 666 WP_338693633.1 response regulator transcription factor Regulator
  V2W30_RS03760 (V2W30_03760) - 775306..776658 (-) 1353 WP_338693635.1 sensor histidine kinase -
  V2W30_RS03765 (V2W30_03765) - 776822..777553 (-) 732 WP_338693636.1 TetR/AcrR family transcriptional regulator -
  V2W30_RS03770 (V2W30_03770) - 777730..778191 (+) 462 WP_338693637.1 nitroreductase/quinone reductase family protein -
  V2W30_RS03775 (V2W30_03775) - 778265..779488 (-) 1224 WP_338693638.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23983.74 Da        Isoelectric Point: 4.8076

>NTDB_id=854548 V2W30_RS03755 WP_338693633.1 774644..775309(-) (vraR) [Streptomyces sp. Q6]
MIRVLLADDQSLVRAGFKALLDAQGDIEVAGEASDGDEAVRLVRELKPDVVLMDIRMPLLDGLAATRRISGEPDLAEVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIAEFAARSKEPSAVASLSELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=854548 V2W30_RS03755 WP_338693633.1 774644..775309(-) (vraR) [Streptomyces sp. Q6]
TTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTCCGCGCCGGATTCAAGGCACTCCTGGACGCGCAGGGCGACAT
CGAGGTCGCGGGCGAGGCATCCGACGGCGACGAAGCGGTGCGTCTGGTCCGGGAGTTGAAGCCGGACGTGGTGCTGATGG
ACATCCGGATGCCGCTGCTCGACGGGCTCGCCGCGACCCGCCGGATCAGCGGGGAACCGGACCTGGCGGAGGTGAAGGTC
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGGGCCTCGGGATTCCTCGTCAAGGA
CACCGAGCCGGAGGAGCTGCTCCGGGCGGTCCGGGCCGTGGTGCACGGCGACGCGCTGCTCTCGCCCGGGGTCACACGGC
GGCTCATCGCCGAGTTCGCGGCCCGCTCCAAGGAGCCGTCGGCCGTCGCGTCGCTGTCCGAACTGACCGAGCGGGAGCGG
GAGGTGATGGCGCTCGTCGGGATCGGCCTGTCCAACGAGGAGATCGCGCGCCGCCTGGTCGTCAGCCCGCTCACGGCGAA
GACCCATGTCAGCCGCACCATGGTGAAACTGGGCGCCCGCGACCGGGCCCAACTGGTCGTCCTCGCCTACGAGTCGGGGC
TCGTGCGGCCCGGATGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

97.738

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.889

100

0.376