Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QUE37_RS05945 Genome accession   NZ_AP027404
Coordinates   1042314..1043438 (+) Length   374 a.a.
NCBI ID   WP_286347796.1    Uniprot ID   -
Organism   Escherichia coli strain EC416 isolate EC416     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1037314..1048438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE37_RS05920 (MUTS2_11290) mscL 1037440..1037850 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  QUE37_RS05925 (MUTS2_11300) trkA 1037980..1039356 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  QUE37_RS05930 (MUTS2_11310) rsmB 1039378..1040667 (-) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QUE37_RS05935 (MUTS2_11320) fmt 1040713..1041660 (-) 948 WP_286347795.1 methionyl-tRNA formyltransferase -
  QUE37_RS05940 (MUTS2_11330) def 1041675..1042184 (-) 510 WP_000114984.1 peptide deformylase -
  QUE37_RS05945 (MUTS2_11340) dprA 1042314..1043438 (+) 1125 WP_286347796.1 DNA-protecting protein DprA Machinery gene
  QUE37_RS05950 (MUTS2_11350) smg 1043410..1043883 (+) 474 WP_000460680.1 DUF494 family protein Smg -
  QUE37_RS05955 (MUTS2_11360) yrdD 1043912..1044454 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  QUE37_RS05960 (MUTS2_11370) tsaC 1044459..1045031 (+) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  QUE37_RS05965 (MUTS2_11380) aroE 1045036..1045854 (+) 819 WP_000451243.1 shikimate dehydrogenase -
  QUE37_RS05970 (MUTS2_11390) yrdB 1045851..1046108 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  QUE37_RS05975 (MUTS2_11400) yrdA 1046084..1046638 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41044.01 Da        Isoelectric Point: 6.4381

>NTDB_id=85403 QUE37_RS05945 WP_286347796.1 1042314..1043438(+) (dprA) [Escherichia coli strain EC416 isolate EC416]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPRALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFSRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=85403 QUE37_RS05945 WP_286347796.1 1042314..1043438(+) (dprA) [Escherichia coli strain EC416 isolate EC416]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCCGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCTCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388

Multiple sequence alignment