Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6U69_RS09920 Genome accession   NZ_CP145867
Coordinates   2125431..2127368 (-) Length   645 a.a.
NCBI ID   WP_410533804.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2120431..2132368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS09890 (V6U69_09880) spx 2120660..2121058 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  V6U69_RS09895 (V6U69_09885) recA 2121226..2122365 (-) 1140 WP_002889600.1 recombinase RecA Machinery gene
  V6U69_RS09900 (V6U69_09890) cinA 2122406..2123671 (-) 1266 WP_410533800.1 competence/damage-inducible protein A Machinery gene
  V6U69_RS09905 (V6U69_09895) - 2123768..2124322 (-) 555 WP_073951167.1 DNA-3-methyladenine glycosylase I -
  V6U69_RS09910 (V6U69_09900) ruvA 2124331..2124921 (-) 591 WP_013989915.1 Holliday junction branch migration protein RuvA Machinery gene
  V6U69_RS09915 (V6U69_09905) - 2125079..2125300 (-) 222 WP_410533802.1 hypothetical protein -
  V6U69_RS09920 (V6U69_09910) hexB 2125431..2127368 (-) 1938 WP_410533804.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6U69_RS09925 (V6U69_09915) - 2127420..2127725 (-) 306 WP_410533806.1 hypothetical protein -
  V6U69_RS09930 (V6U69_09920) - 2127904..2128341 (+) 438 WP_410533808.1 LytTR family DNA-binding domain-containing protein -
  V6U69_RS09935 (V6U69_09925) - 2128338..2128793 (+) 456 WP_060972120.1 DUF3021 domain-containing protein -
  V6U69_RS09940 (V6U69_09930) hexA 2128827..2131385 (-) 2559 WP_410533810.1 DNA mismatch repair protein MutS Machinery gene
  V6U69_RS09945 (V6U69_09935) - 2131378..2131737 (-) 360 WP_073689443.1 YlbF family regulator -
  V6U69_RS09950 (V6U69_09940) argR 2131737..2132165 (-) 429 WP_171963598.1 arginine repressor -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72316.36 Da        Isoelectric Point: 5.2797

>NTDB_id=854010 V6U69_RS09920 WP_410533804.1 2125431..2127368(-) (hexB) [Streptococcus salivarius strain KSS10]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQSDVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLKEQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRSADESDSEHEKLDYKNKSKMKRMLENLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=854010 V6U69_RS09920 WP_410533804.1 2125431..2127368(-) (hexB) [Streptococcus salivarius strain KSS10]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATTACAGACAATGGCGAAGGAATGGCTCAATCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACGGCGGCTGATGGAGAAGCCTATGGGACTAAACTGGTTGCCAAGGGTGGGGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACTTATTTTATAATACCCCTGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCCGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAAGTTGCCTT
CACCTTGCTCAATGACGGCCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGCCAAGCTATTGCCGGGATTTATG
GTTTAACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGCTATGTAAGCCTTCCT
GAATTAACTCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCGGTTATTGATATTCAAATTGATCCCTATT
TGGCTGATGTTAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCTCTTATTAGCTCT
GCCATTGCTCAAAGTCTTAAAGAGCAGGATTTAATTCCAGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AACTAAGCCGGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCACTTGTATCAGAGTCTCCAGTTTCATCGGTAGAAAACAAACCGCAACCT
TCTGTTAAACAAGCACAACGTTCAGCAGATGAAAGTGATAGTGAACACGAAAAACTTGATTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAAATCTGGACAATGAGGAAACATCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTCTTTGCTCAAGGACAAGGTGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TATCGCGAAAAGATTGGTGAGGTTGACAGTAGTTTACAACAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCGGA
TTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACACCTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCTGCAGTCTATGAAATGTGCGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTCAAAACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTCGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTCACGGAC
GTCCTGTACTTGTCAACTTTACAAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACCAGTCTACGT
GACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(446-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.031

100

0.71