Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   V6U69_RS03995 Genome accession   NZ_CP145867
Coordinates   886339..888123 (+) Length   594 a.a.
NCBI ID   WP_070838932.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 881339..893123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS03970 (V6U69_03970) - 881867..882724 (+) 858 WP_410534225.1 transketolase -
  V6U69_RS03975 (V6U69_03975) - 882721..883647 (+) 927 WP_073689326.1 transketolase family protein -
  V6U69_RS03980 (V6U69_03980) sdaAA 883739..884608 (-) 870 WP_021147208.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  V6U69_RS03985 (V6U69_03985) sdaAB 884621..885292 (-) 672 WP_070577329.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  V6U69_RS03990 (V6U69_03990) - 885572..886267 (+) 696 WP_070577328.1 YjjG family noncanonical pyrimidine nucleotidase -
  V6U69_RS03995 (V6U69_03995) uvrC 886339..888123 (+) 1785 WP_070838932.1 excinuclease ABC subunit UvrC Machinery gene
  V6U69_RS04000 (V6U69_04000) - 888436..888675 (+) 240 WP_002885362.1 protein rep -
  V6U69_RS04005 (V6U69_04005) - 888688..889011 (-) 324 WP_037599177.1 potassium channel family protein -
  V6U69_RS04010 (V6U69_04010) cls 889670..891220 (+) 1551 WP_410534346.1 cardiolipin synthase -
  V6U69_RS04015 (V6U69_04015) - 891301..891813 (+) 513 WP_080610607.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68558.94 Da        Isoelectric Point: 9.3882

>NTDB_id=853956 V6U69_RS03995 WP_070838932.1 886339..888123(+) (uvrC) [Streptococcus salivarius strain KSS10]
MNDLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDDKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDLAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRKELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKHFK
SMTAIQKASAEDIQALGIPEKVAEALLDKLNDNN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=853956 V6U69_RS03995 WP_070838932.1 886339..888123(+) (uvrC) [Streptococcus salivarius strain KSS10]
ATGAATGATCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCGGGGTGCTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACTAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCCAATATTGAGGCCCTGCTTTTGGAAATTAAT
CTTATCCAAGAGAATATGCCTAAATTCAACATCCGCCTCAAGGATGACAAGTCTTATCCATTTATCAAGATTACTAAGGA
GCTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGCGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CGGCCAATGAAATCAAGAAGCTTTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCGGCCAATAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAAGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAATCAGCTTAAGGCCAAGATGAAGGATATGTCTGACCAGATGG
AGTTTGAGCGTGCTGCGGAGTATCGCGATTTGATTGAGGCGGTTTCGACGCTTAGGACCAAGCAAAGGGTTATCCGTCAA
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGATAAGGGGTGGATGTGTGTTCAGGTTTTCTTTGTTCGCCAAGG
GAAACTCATTCAGCGTGATGTCAATATGTTCCCTTATTATAATGATGCTGAGGAAGATTTCCTAACCTATATGGGTCAGT
TTTATCTGGATAGTCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGAGACATTGATCAAGAGTCTGTTGAGGCTCTA
GTTGGAGATGAGGTCAAGGTCTTTAAACCTCAACGTGGAGAGAAGAAGCAGTTGGTTAATCTGGCGACGAAAAATGCCCG
CGTCAGTTTGACCCAAAAATTTGATCTCCTCGAAAAAGACTTGGCTAAGACCCAAGGAGCTATTGAAAATCTAGGCAAAC
TCATGGGGATTCCGACACCGGTCCGTATCGAGTCTTTCGATAACTCTAATATCATGGGAACTAGCCCTGTCTCTGCCATG
GTTGTCTTTGAAAATGGTAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACTGTTGAAGGCCCTGACGATTA
TGCCAGTATGCGTGAGGTCATTCGTCGTCGCTATAGTCGTGTCAAACGTGATGGTCTAACGCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTAGCCAAGGATGTGCTTCGCAAGGAACTCAATCTATCTATCCCAGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTTTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGTCAAGTCCGTAGTA
AGAATAGTTTCAGTTCTAAACTTGATGGCGTGGAGGGGTTAGGACCTAAGCGCAAACAAAAACTTCTCAAACACTTCAAG
TCTATGACAGCTATCCAAAAAGCCAGTGCCGAAGACATTCAAGCTCTTGGAATCCCTGAAAAAGTAGCAGAGGCTCTGTT
AGATAAATTAAATGATAACAATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

Helix-hairpin-helix domain (HHH_5)

(540-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.65

99.495

0.763
  uvrC Streptococcus pneumoniae R6

76.311

99.495

0.759
  uvrC Streptococcus pneumoniae D39

76.311

99.495

0.759