Detailed information NTG0853793

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U68_RS00320
• Genome accession: NZ_CP145866
• Coordinates: 52000..54531 (+)
• Length: 843 a.a.
• NCBI ID: WP_410532072.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 47000..59531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS00290 (V6U68_00290)	-	48155..48349 (+)	195	WP_004181980.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
V6U68_RS00295 (V6U68_00295)	-	48376..48576 (+)	201	WP_013989905.1	hypothetical protein	-
V6U68_RS00300 (V6U68_00300)	-	48569..48724 (+)	156	WP_013989906.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
V6U68_RS00305 (V6U68_00305)	argS	49347..51038 (-)	1692	WP_073689444.1	arginine--tRNA ligase	-
V6U68_RS00310 (V6U68_00310)	argR	51193..51621 (+)	429	WP_171963598.1	arginine repressor	-
V6U68_RS00315 (V6U68_00315)	-	51621..51980 (+)	360	WP_073689443.1	YlbF family regulator	-
V6U68_RS00320 (V6U68_00320)	hexA	52000..54531 (+)	2532	WP_410532072.1	DNA mismatch repair protein MutS	Machinery gene
V6U68_RS00325 (V6U68_00325)	-	54565..55020 (-)	456	WP_060972120.1	DUF3021 domain-containing protein	-
V6U68_RS00330 (V6U68_00330)	-	55017..55454 (-)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
V6U68_RS00335 (V6U68_00335)	-	55633..55938 (+)	306	WP_155198552.1	hypothetical protein	-
V6U68_RS00340 (V6U68_00340)	hexB	55990..57927 (+)	1938	WP_155198551.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U68_RS00345 (V6U68_00345)	-	58058..58279 (+)	222	WP_037597288.1	hypothetical protein	-
V6U68_RS00350 (V6U68_00350)	ruvA	58437..59027 (+)	591	WP_037599413.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94596.63 Da
• Isoelectric Point: 4.6941

>NTDB_id=853793 V6U68_RS00320 WP_410532072.1 52000..54531(+) (hexA) [Streptococcus salivarius strain KSS9]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADKPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDALSRLLQELDALPELERLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKERAASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNSLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSPQEKSATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=853793 V6U68_RS00320 WP_410532072.1 52000..54531(+) (hexA) [Streptococcus salivarius strain KSS9]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTTTCGGATGGGGGATTTTTACGAATTATT
TTACGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCAGATAAACCCATTC
CTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTTGAGATGGGCTACAAAGTAGCCATTGCT
GAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGCTCTAAACCTGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGGTTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTATCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCAGTTTGCAGTGAAATTCAGAATCTTAAG
GCACGTGAAGTAGTGGTTGGTTATGATTTACCTGAAGCTGACGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTCTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGTTTGACAGATTTGGAAAGCAGTGTGGCGGGTAAAC
TTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAAGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTGGAAAATGCTAGAACGGGCAAGAAACACGGATCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTTGGATTGATCGTCCTTTAGTGAATCAAG
CCACTATCACCGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTTGAGCGTAGTGACTTGACTGAGAGTCTA
AAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGCTAATCCAAAAGATTTGATTCAGCTAGG
TCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGAGTCTTTTAATGACGATGCCTTGTCACGTCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGATTGATTCGGTCGGCTATTGATCCAGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGAACCTCATGGATTGCAGA
TATCGAAGCCAAAGAACGTGCAGCGTCTGGTATTACAACACTAAAGATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACTCTGAAAAATTCAGAGCGATTTGGA
ACTGCTGAGTTGGCTAAAATTGAAGGTGAAATGCTTGAGGCGCGTGAAAAATCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCCATTGCGACCGTCGATGTGCTTC
AAAGTTTGGCTGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATCGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATTACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGTCAGTTAGCCTTGTCAGTAGTTATGGCTC
AGATGGGGTCTTATGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCTACCTATGATGGTATGGCCTTAGCTCAGTCTATTATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAACAGTTTGACACAC
CTTGTAAACGTTCATGTGGCGACACTTGAAAAGGACGGTGAAGTGACTTTCCTTCACAAGATTGTCGATGGACCAGCCGA
CAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AACTAGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAATCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTGCGTGATTTAGATATTTACAACAT
GACACCTATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (117-230)

• MutS domain III (MutS_III) (247-537)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain I (MutS_I) (1-109)

• MutS domain V (MutS_V) (590-776)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.784	100	0.738
mutS	Pseudomonas stutzeri strain ATCC 17587	36.311	100	0.371