Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   V6U67_RS07885 Genome accession   NZ_CP145865
Coordinates   1735384..1737489 (-) Length   701 a.a.
NCBI ID   WP_070579628.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1730384..1742489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS07855 (V6U67_07865) trmB 1730968..1731609 (-) 642 WP_073687300.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  V6U67_RS07860 (V6U67_07870) ccrZ 1731619..1732410 (-) 792 WP_002884270.1 cell cycle regulator CcrZ -
  V6U67_RS07865 (V6U67_07875) pptB 1732468..1733505 (-) 1038 WP_048790351.1 ABC transporter permease Regulator
  V6U67_RS07870 (V6U67_07880) pptA 1733502..1734233 (-) 732 WP_048674716.1 ABC transporter ATP-binding protein Regulator
  V6U67_RS07875 (V6U67_07885) - 1734298..1734717 (+) 420 WP_048790350.1 HIT family protein -
  V6U67_RS07880 (V6U67_07890) - 1734714..1735013 (+) 300 WP_272125628.1 hypothetical protein -
  V6U67_RS07885 (V6U67_07895) clpE 1735384..1737489 (-) 2106 WP_070579628.1 AAA family ATPase Regulator
  V6U67_RS07890 (V6U67_07900) - 1738205..1738459 (-) 255 WP_014634942.1 Txe/YoeB family addiction module toxin -
  V6U67_RS07895 (V6U67_07905) - 1738463..1738717 (-) 255 WP_013991075.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  V6U67_RS07900 (V6U67_07910) - 1738859..1739950 (-) 1092 WP_037611898.1 nucleotidyltransferase -
  V6U67_RS07905 (V6U67_07915) - 1739957..1740697 (-) 741 WP_022496427.1 class I SAM-dependent DNA methyltransferase -
  V6U67_RS07910 (V6U67_07920) rsfS 1740902..1741255 (-) 354 WP_014632696.1 ribosome silencing factor -
  V6U67_RS07915 (V6U67_07925) yqeK 1741278..1741868 (-) 591 WP_037611900.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77333.27 Da        Isoelectric Point: 4.7718

>NTDB_id=853756 V6U67_RS07885 WP_070579628.1 1735384..1737489(-) (clpE) [Streptococcus salivarius strain KSS8]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=853756 V6U67_RS07885 WP_070579628.1 1735384..1737489(-) (clpE) [Streptococcus salivarius strain KSS8]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGACGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCAGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGACGCCGGTGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCAC
AAGCCATCGTAAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGCGATGGCCAAGGCTCTAAAGGTCTTGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCAGCTCTTGCTCGTCGTTTCAATGAAGTTAAGGTTAATGCTCCTTCTGCTGAAGATACCTTCAAGATTCTCCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAAGCAGCAGTAGATTTCTCTGTCC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAT
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATGCTAAAGTTCGCATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGCAGACCTTAAAG
TCACAGCAACTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGTTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATTCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTTATCA
CACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.648

100

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

49.002

92.867

0.455
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpC Bacillus subtilis subsp. subtilis str. 168

45.666

92.154

0.421
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus thermophilus LMD-9

43.436

88.017

0.382
  clpC Streptococcus thermophilus LMG 18311

42.973

88.302

0.379
  clpC Streptococcus mutans UA159

42.332

89.301

0.378