Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V6U66_RS03330 Genome accession   NZ_CP145864
Coordinates   641351..641995 (+) Length   214 a.a.
NCBI ID   WP_002884791.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 636351..646995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS03310 (V6U66_03310) stkP/pknB 636708..638588 (+) 1881 WP_049527645.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  V6U66_RS03315 (V6U66_03315) - 638734..639492 (+) 759 WP_049527642.1 potassium channel family protein -
  V6U66_RS03320 (V6U66_03320) liaF 639656..640354 (+) 699 WP_002886862.1 cell wall-active antibiotics response protein LiaF -
  V6U66_RS03325 (V6U66_03325) - 640351..641361 (+) 1011 WP_013990239.1 sensor histidine kinase -
  V6U66_RS03330 (V6U66_03330) vraR 641351..641995 (+) 645 WP_002884791.1 response regulator transcription factor Regulator
  V6U66_RS03345 (V6U66_03345) rimM 642690..643208 (+) 519 WP_002884411.1 ribosome maturation factor RimM -
  V6U66_RS03350 (V6U66_03350) trmD 643198..643917 (+) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  V6U66_RS03355 (V6U66_03355) - 643919..644917 (+) 999 WP_002886866.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23977.31 Da        Isoelectric Point: 4.5814

>NTDB_id=853601 V6U66_RS03330 WP_002884791.1 641351..641995(+) (vraR) [Streptococcus salivarius strain KSS7]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=853601 V6U66_RS03330 WP_002884791.1 641351..641995(+) (vraR) [Streptococcus salivarius strain KSS7]
ATGTCGAATAAGATTAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTAGTTGGGGAGGCAGGGAATGGTCGAGAGGGTGTCGATCTTGCCTTGGAACTGCGTCCGGATGTCG
TCGTTATGGACCTTGTTATGCCTGAATTGGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGTGCTAAAGGCTATATGCTTAA
AACCAGCAGTGCGGCAGAGATTCTTAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTGACGGCACGTGAACGTGATATCTTGGCCCTTTTG
GCTAAGGGGTATGACAATCAAACTATTGCTAATGAGCTATTTATTTCATTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCAGTCGTTTATGCCTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379