Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V6U65_RS07070 Genome accession   NZ_CP145863
Coordinates   1571078..1571722 (-) Length   214 a.a.
NCBI ID   WP_002891417.1    Uniprot ID   J7TMS3
Organism   Streptococcus salivarius strain KSS6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1566078..1576722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS07045 (V6U65_07040) - 1568155..1569153 (-) 999 WP_410532288.1 NAD(P)/FAD-dependent oxidoreductase -
  V6U65_RS07050 (V6U65_07045) trmD 1569155..1569874 (-) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  V6U65_RS07055 (V6U65_07050) rimM 1569864..1570382 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  V6U65_RS07070 (V6U65_07065) vraR 1571078..1571722 (-) 645 WP_002891417.1 response regulator transcription factor Regulator
  V6U65_RS07075 (V6U65_07070) - 1571712..1572722 (-) 1011 WP_002891418.1 sensor histidine kinase -
  V6U65_RS07080 (V6U65_07075) liaF 1572719..1573417 (-) 699 WP_073685667.1 cell wall-active antibiotics response protein LiaF -
  V6U65_RS07085 (V6U65_07080) - 1573581..1574339 (-) 759 WP_410532290.1 potassium channel family protein -
  V6U65_RS07090 (V6U65_07085) stkP/pknB 1574485..1576359 (-) 1875 WP_410532291.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5814

>NTDB_id=853510 V6U65_RS07070 WP_002891417.1 1571078..1571722(-) (vraR) [Streptococcus salivarius strain KSS6]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEASNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=853510 V6U65_RS07070 WP_002891417.1 1571078..1571722(-) (vraR) [Streptococcus salivarius strain KSS6]
ATGTCGAATAAGATAAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCCTGAATCTCCA
AGGAGATGTCGAAGTGGTTGGAGAAGCGAGCAATGGCCGAGAAGGTGTTGACCTTGCCCTGGAACTTCGTCCAGATGTCG
TCGTAATGGACCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCAGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGTGCTAAAGGTTATATGCTTAA
AACTAGCAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCACGATAGCCACCCGGACCTACACGACGACTTGACGGCACGTGAACGTGATATCTTGGCGCTTTTG
GCTAAGGGTTATGACAATCAAACCATTGCTAATGAGCTATTTATTTCGTTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTTGTTTATGCCTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TMS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379