Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6U65_RS00330 Genome accession   NZ_CP145863
Coordinates   53644..55581 (+) Length   645 a.a.
NCBI ID   WP_037603795.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 48644..60581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS00300 (V6U65_00300) argR 48847..49275 (+) 429 WP_170314548.1 arginine repressor -
  V6U65_RS00305 (V6U65_00305) - 49275..49634 (+) 360 WP_002889586.1 YlbF family regulator -
  V6U65_RS00310 (V6U65_00310) hexA 49654..52185 (+) 2532 WP_371482835.1 DNA mismatch repair protein MutS Machinery gene
  V6U65_RS00315 (V6U65_00315) - 52219..52674 (-) 456 WP_037603799.1 DUF3021 domain-containing protein -
  V6U65_RS00320 (V6U65_00320) - 52671..53108 (-) 438 WP_013989911.1 LytTR family DNA-binding domain-containing protein -
  V6U65_RS00325 (V6U65_00325) - 53287..53592 (+) 306 WP_037603797.1 hypothetical protein -
  V6U65_RS00330 (V6U65_00330) hexB 53644..55581 (+) 1938 WP_037603795.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6U65_RS00335 (V6U65_00335) - 55712..55933 (+) 222 WP_002886321.1 hypothetical protein -
  V6U65_RS00340 (V6U65_00340) ruvA 56091..56681 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  V6U65_RS00345 (V6U65_00345) - 56690..57244 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  V6U65_RS00350 (V6U65_00350) cinA 57341..58609 (+) 1269 WP_048790895.1 competence/damage-inducible protein A Machinery gene
  V6U65_RS00355 (V6U65_00355) recA 58645..59784 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  V6U65_RS00360 (V6U65_00360) spx 59951..60349 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72289.34 Da        Isoelectric Point: 5.2797

>NTDB_id=853449 V6U65_RS00330 WP_037603795.1 53644..55581(+) (hexB) [Streptococcus salivarius strain KSS6]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQSDVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRSVDEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=853449 V6U65_RS00330 WP_037603795.1 53644..55581(+) (hexB) [Streptococcus salivarius strain KSS6]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTAGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAATCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTAAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGATATGGCTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCTTACT
TGGCCGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCA
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTACGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCAGAGTCACCAGTTTCATCGGTAGAAAATAAACCGCAACCT
TCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TATCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCAGA
CTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAACAACACTTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTCACGGAC
GTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGTCTACGT
GACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(446-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.665

100

0.709