Detailed information NTG0853448

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U65_RS00310
• Genome accession: NZ_CP145863
• Coordinates: 49654..52185 (+)
• Length: 843 a.a.
• NCBI ID: WP_371482835.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS6
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 44654..57185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS00285 (V6U65_00285)	-	44992..45840 (+)	849	WP_175060959.1	hypothetical protein	-
V6U65_RS00290 (V6U65_00290)	-	45880..46125 (+)	246	Protein_36	adenylosuccinate lyase	-
V6U65_RS00295 (V6U65_00295)	argS	47001..48692 (-)	1692	WP_002889584.1	arginine--tRNA ligase	-
V6U65_RS00300 (V6U65_00300)	argR	48847..49275 (+)	429	WP_170314548.1	arginine repressor	-
V6U65_RS00305 (V6U65_00305)	-	49275..49634 (+)	360	WP_002889586.1	YlbF family regulator	-
V6U65_RS00310 (V6U65_00310)	hexA	49654..52185 (+)	2532	WP_371482835.1	DNA mismatch repair protein MutS	Machinery gene
V6U65_RS00315 (V6U65_00315)	-	52219..52674 (-)	456	WP_037603799.1	DUF3021 domain-containing protein	-
V6U65_RS00320 (V6U65_00320)	-	52671..53108 (-)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
V6U65_RS00325 (V6U65_00325)	-	53287..53592 (+)	306	WP_037603797.1	hypothetical protein	-
V6U65_RS00330 (V6U65_00330)	hexB	53644..55581 (+)	1938	WP_037603795.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U65_RS00335 (V6U65_00335)	-	55712..55933 (+)	222	WP_002886321.1	hypothetical protein	-
V6U65_RS00340 (V6U65_00340)	ruvA	56091..56681 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94607.61 Da
• Isoelectric Point: 4.6298

>NTDB_id=853448 V6U65_RS00310 WP_371482835.1 49654..52185(+) (hexA) [Streptococcus salivarius strain KSS6]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVVAETNHYVRPIFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=853448 V6U65_RS00310 WP_371482835.1 49654..52185(+) (hexA) [Streptococcus salivarius strain KSS6]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAATGCTGATAATCCTATTC
CCATGGCTGGTGTTCCTTATCATTCAGCTCAAGCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTTGGTCAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTAGAAAATGCTAGAACGGGCAAGAAACACGGATCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTTGGATTGATCGTCCTTTAGTGAATCAAG
CCACTATCACCGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTTGAGCGGAGTGACTTGACTGAGAGTCTA
AAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGCTAATCCAAAAGATTTGATTCAGTTAGG
TCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGAGTCTTTTAATGACGATGCCTTGTCACGTCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCAGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGAACCTCATGGATCGCAGA
TATCGAAGCTAAAGAACGTGAAGCATCTGGTATTACAACACTAAAGATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACTCTGAAAAATTCAGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAAATTGAAGGTGAGATGCTTGAGGCGCGTGAAAAATCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAACAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCTATTGCGACAGTCGATGTGCTTC
AGAGTCTAGCTGTTGTAGCAGAGACCAATCATTATGTTCGCCCTATTTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGCCGTCATGCAGTGGTTGAGAAGGTTATGGGCGTTCAAGAATACATTCCAAACACCATTACCTTTGATAGTCAGACCAA
TATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTCAGTTAGCCTTGTCAGTAGTTATGGCTC
AGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCTATCTATACACGTATTGGTGCTGCAGAT
GACCTGATTTCAGGGCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAACCAGGCTATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCTACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCGACCCATTATCATGAGTTGACAGCTCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGCGAAGTGACCTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AACTAGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTGCGTGATTTAGATATTTACAACAT
GACACCTATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (117-230)

• MutS domain III (MutS_III) (247-537)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain V (MutS_V) (590-776)

• MutS domain I (MutS_I) (1-109)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.377	100	0.744
mutS	Pseudomonas stutzeri strain ATCC 17587	35.963	100	0.368