Detailed information NTG0853227

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U63_RS00300
• Genome accession: NZ_CP145861
• Coordinates: 48860..51391 (+)
• Length: 843 a.a.
• NCBI ID: WP_371212499.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS3
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 43860..56391

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U63_RS00280 (V6U63_00280)	purB	44035..45333 (+)	1299	WP_195914835.1	adenylosuccinate lyase	-
V6U63_RS00285 (V6U63_00285)	argS	46207..47898 (-)	1692	WP_195914834.1	arginine--tRNA ligase	-
V6U63_RS00290 (V6U63_00290)	argR	48053..48481 (+)	429	WP_171963651.1	arginine repressor	-
V6U63_RS00295 (V6U63_00295)	-	48481..48840 (+)	360	WP_002889586.1	YlbF family regulator	-
V6U63_RS00300 (V6U63_00300)	hexA	48860..51391 (+)	2532	WP_371212499.1	DNA mismatch repair protein MutS	Machinery gene
V6U63_RS00305 (V6U63_00305)	-	51425..51880 (-)	456	WP_045768436.1	DUF3021 domain-containing protein	-
V6U63_RS00310 (V6U63_00310)	-	51877..52314 (-)	438	WP_073686198.1	LytTR family DNA-binding domain-containing protein	-
V6U63_RS00315 (V6U63_00315)	-	52493..52798 (+)	306	WP_002886319.1	hypothetical protein	-
V6U63_RS00320 (V6U63_00320)	hexB	52848..54791 (+)	1944	WP_022495805.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U63_RS00325 (V6U63_00325)	-	54922..55143 (+)	222	WP_022495804.1	hypothetical protein	-
V6U63_RS00330 (V6U63_00330)	ruvA	55301..55891 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94635.63 Da
• Isoelectric Point: 4.6360

>NTDB_id=853227 V6U63_RS00300 WP_371212499.1 48860..51391(+) (hexA) [Streptococcus salivarius strain KSS3]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERYG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSHTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=853227 V6U63_RS00300 WP_371212499.1 48860..51391(+) (hexA) [Streptococcus salivarius strain KSS3]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGGAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTACCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTTGGTCAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAGAACGGGCAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGCACTTGGATTGATCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGCTTAGCCAGTCGAGTTTCCTTTGGCAAGGCTAATCCTAAAGATTTGATTCAACTAGG
TCATACCTTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCAGCTATTGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATTGCGGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTATGGA
ACCGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTCATCAACGCTCGAATATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCCATTGCGACAGTCGATGTTCTTC
AGAGCTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCATACCAA
TGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTCAGTTGGCTTTGTCAGTCGTTATGGCTC
AGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AACTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAAGTCATGATGGCTGTAGCGGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain I (MutS_I) (1-109)

• MutS domain III (MutS_III) (247-537)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.731	100	0.365