Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   V6U62_RS02080 Genome accession   NZ_CP145860
Coordinates   394121..396226 (+) Length   701 a.a.
NCBI ID   WP_410534980.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 389121..401226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS02050 (V6U62_02040) yhbY 389342..389659 (+) 318 WP_037611902.1 ribosome assembly RNA-binding protein YhbY -
  V6U62_RS02055 (V6U62_02045) - 389767..390399 (+) 633 WP_002884372.1 nicotinate-nucleotide adenylyltransferase -
  V6U62_RS02060 (V6U62_02050) yqeK 390396..390986 (+) 591 WP_037611900.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  V6U62_RS02065 (V6U62_02055) rsfS 391009..391362 (+) 354 WP_014632696.1 ribosome silencing factor -
  V6U62_RS02070 (V6U62_02060) - 391567..392307 (+) 741 WP_022496427.1 class I SAM-dependent DNA methyltransferase -
  V6U62_RS02075 (V6U62_02065) - 392314..393405 (+) 1092 WP_410534982.1 nucleotidyltransferase -
  V6U62_RS02080 (V6U62_02070) clpE 394121..396226 (+) 2106 WP_410534980.1 AAA family ATPase Regulator
  V6U62_RS02085 (V6U62_02075) - 396618..397115 (+) 498 WP_245085241.1 hypothetical protein -
  V6U62_RS02090 (V6U62_02080) - 397134..397478 (+) 345 WP_155123768.1 hypothetical protein -
  V6U62_RS02095 (V6U62_02085) - 397516..397866 (+) 351 WP_183139907.1 ribonuclease -
  V6U62_RS02100 (V6U62_02090) - 397883..398182 (-) 300 WP_022496188.1 hypothetical protein -
  V6U62_RS02105 (V6U62_02095) - 398179..398598 (-) 420 WP_002891660.1 HIT family protein -
  V6U62_RS02110 (V6U62_02100) pptA 398663..399394 (+) 732 WP_022496187.1 ABC transporter ATP-binding protein Regulator
  V6U62_RS02115 (V6U62_02105) pptB 399391..400428 (+) 1038 WP_022496186.1 ABC transporter permease Regulator

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77333.27 Da        Isoelectric Point: 4.7718

>NTDB_id=853147 V6U62_RS02080 WP_410534980.1 394121..396226(+) (clpE) [Streptococcus salivarius strain KSS2]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEAEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=853147 V6U62_RS02080 WP_410534980.1 394121..396226(+) (clpE) [Streptococcus salivarius strain KSS2]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGACGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCAGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGACGCCGGTGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCAC
AAGCCATCGTAAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGCGATGGCCAAGGCTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAGGATGAATACCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTTAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACCTTCAAGATTCTTCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAAGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGCTGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGAAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATTGAACGTCTGAAAGACATGGGTCACCGTTTGCAAACCAAGGTTATCGGTCAAGATAAAGCTGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGACGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

AAA lid domain (AAA_lid_9)

(257-352)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

47.218

100

0.472
  clpC Lactococcus lactis subsp. cremoris KW2

49.923

93.153

0.465
  clpE Streptococcus pneumoniae D39

49.224

91.869

0.452
  clpE Streptococcus pneumoniae R6

49.224

91.869

0.452
  clpE Streptococcus pneumoniae Rx1

49.224

91.869

0.452
  clpE Streptococcus pneumoniae TIGR4

48.989

91.726

0.449
  clpC Bacillus subtilis subsp. subtilis str. 168

46.296

92.439

0.428
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.867

0.392
  clpC Streptococcus pneumoniae TIGR4

44.013

88.16

0.388
  clpC Streptococcus pneumoniae Rx1

44.013

88.16

0.388
  clpC Streptococcus pneumoniae D39

44.013

88.16

0.388
  clpC Streptococcus thermophilus LMD-9

43.274

88.017

0.381
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.308

89.016

0.377