Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V6S31_RS10390 Genome accession   NZ_CP145689
Coordinates   2160817..2161473 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain S1-KEN-05-A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2155817..2166473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6S31_RS10360 (V6S31_10340) dcyD 2156696..2157682 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  V6S31_RS10365 (V6S31_10345) tcyL 2157697..2158365 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  V6S31_RS10370 (V6S31_10350) tcyN 2158362..2159114 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V6S31_RS10375 (V6S31_10355) sdiA 2159344..2160066 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  V6S31_RS10380 (V6S31_10360) yecF 2160134..2160358 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  V6S31_RS10385 (V6S31_10365) yecU 2160345..2160521 (-) 177 WP_001307856.1 protein YecU -
  V6S31_RS10390 (V6S31_10370) letA 2160817..2161473 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V6S31_RS10395 (V6S31_10375) uvrC 2161470..2163302 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  V6S31_RS10400 (V6S31_10380) pgsA 2163359..2163907 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V6S31_RS10420 (V6S31_10400) yecA 2164556..2165221 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=852278 V6S31_RS10390 WP_000611328.1 2160817..2161473(+) (letA) [Escherichia coli strain S1-KEN-05-A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=852278 V6S31_RS10390 WP_000611328.1 2160817..2161473(+) (letA) [Escherichia coli strain S1-KEN-05-A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482