Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QYR57_RS05060 Genome accession   NZ_CP129327
Coordinates   1037307..1038536 (-) Length   409 a.a.
NCBI ID   WP_367562083.1    Uniprot ID   -
Organism   Streptococcus iniae strain Si 4-21     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1017947..1066943 1037307..1038536 within 0


Gene organization within MGE regions


Location: 1017947..1066943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYR57_RS04960 (QYR57_04960) - 1017947..1019101 (-) 1155 WP_003099772.1 ABC transporter ATP-binding protein -
  QYR57_RS04965 (QYR57_04965) murB 1019136..1020029 (-) 894 WP_003099774.1 UDP-N-acetylmuramate dehydrogenase -
  QYR57_RS04970 (QYR57_04970) - 1020284..1021450 (+) 1167 WP_367561414.1 IS30 family transposase -
  QYR57_RS04975 (QYR57_04975) folK 1021702..1022193 (-) 492 WP_367562075.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  QYR57_RS04980 (QYR57_04980) folB 1022190..1022549 (-) 360 WP_003099779.1 dihydroneopterin aldolase -
  QYR57_RS04985 (QYR57_04985) folP 1022556..1023356 (-) 801 WP_367562076.1 dihydropteroate synthase -
  QYR57_RS04990 (QYR57_04990) folE 1023366..1023929 (-) 564 WP_003099782.1 GTP cyclohydrolase I FolE -
  QYR57_RS04995 (QYR57_04995) - 1023958..1025217 (-) 1260 WP_003099784.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  QYR57_RS05000 (QYR57_05000) thrB 1025301..1026161 (-) 861 WP_367562077.1 homoserine kinase -
  QYR57_RS05005 (QYR57_05005) - 1026163..1027449 (-) 1287 WP_367562078.1 homoserine dehydrogenase -
  QYR57_RS05010 (QYR57_05010) - 1027634..1028554 (+) 921 WP_367562079.1 polysaccharide deacetylase family protein -
  QYR57_RS05015 (QYR57_05015) - 1028814..1029989 (+) 1176 WP_003099056.1 IS256 family transposase -
  QYR57_RS05025 (QYR57_05025) tnpA 1031507..1031947 (-) 441 WP_003099798.1 IS200/IS605 family transposase -
  QYR57_RS05030 (QYR57_05030) rplL 1032170..1032536 (-) 367 Protein_963 50S ribosomal protein L7/L12 -
  QYR57_RS05035 (QYR57_05035) rplJ 1032600..1033100 (-) 501 WP_367562080.1 50S ribosomal protein L10 -
  QYR57_RS05040 (QYR57_05040) - 1033364..1034317 (-) 954 WP_003098612.1 IS30 family transposase -
  QYR57_RS05045 (QYR57_05045) - 1034463..1035805 (-) 1343 Protein_966 IS3 family transposase -
  QYR57_RS05050 (QYR57_05050) - 1035877..1036590 (-) 714 WP_367562081.1 hypothetical protein -
  QYR57_RS05055 (QYR57_05055) yihA 1036698..1037297 (-) 600 WP_367562082.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QYR57_RS05060 (QYR57_05060) clpX 1037307..1038536 (-) 1230 WP_367562083.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  QYR57_RS05065 (QYR57_05065) - 1038761..1039258 (-) 498 WP_003099817.1 dihydrofolate reductase -
  QYR57_RS05070 (QYR57_05070) - 1039337..1040176 (-) 840 WP_367562084.1 thymidylate synthase -
  QYR57_RS05075 (QYR57_05075) - 1040372..1041544 (+) 1173 WP_367562085.1 hydroxymethylglutaryl-CoA synthase -
  QYR57_RS05080 (QYR57_05080) - 1041534..1042811 (+) 1278 WP_367562086.1 hydroxymethylglutaryl-CoA reductase, degradative -
  QYR57_RS05085 (QYR57_05085) fni 1042835..1043830 (-) 996 WP_003099830.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  QYR57_RS05090 (QYR57_05090) - 1043811..1044830 (-) 1020 WP_367562087.1 phosphomevalonate kinase -
  QYR57_RS05095 (QYR57_05095) mvaD 1044823..1045767 (-) 945 WP_003099837.1 diphosphomevalonate decarboxylase -
  QYR57_RS05100 (QYR57_05100) mvk 1045743..1046627 (-) 885 WP_367562088.1 mevalonate kinase -
  QYR57_RS05105 (QYR57_05105) - 1046758..1048500 (-) 1743 WP_367562089.1 ABC transporter ATP-binding protein -
  QYR57_RS05110 (QYR57_05110) - 1048502..1050223 (-) 1722 WP_003099849.1 ABC transporter ATP-binding protein -
  QYR57_RS05115 (QYR57_05115) - 1050799..1052829 (+) 2031 WP_367562090.1 5'-nucleotidase C-terminal domain-containing protein -
  QYR57_RS05120 (QYR57_05120) - 1052865..1053275 (-) 411 WP_367562101.1 peptide deformylase -
  QYR57_RS05125 (QYR57_05125) gdhA 1053355..1054704 (-) 1350 WP_367561291.1 NADP-specific glutamate dehydrogenase -
  QYR57_RS05130 (QYR57_05130) - 1054838..1056604 (-) 1767 WP_367561292.1 ABC transporter ATP-binding protein -
  QYR57_RS05135 (QYR57_05135) - 1056604..1058347 (-) 1744 Protein_984 ABC transporter ATP-binding protein -
  QYR57_RS05140 (QYR57_05140) - 1058449..1058928 (-) 480 WP_367561293.1 GNAT family N-acetyltransferase -
  QYR57_RS10325 - 1058930..1059139 (-) 210 WP_394812814.1 ABC transporter C-terminal domain-containing protein -
  QYR57_RS05145 (QYR57_05145) - 1059214..1060817 (-) 1604 Protein_987 ABC-F family ATP-binding cassette domain-containing protein -
  QYR57_RS05150 (QYR57_05150) - 1060814..1062022 (-) 1209 WP_367561294.1 CCA tRNA nucleotidyltransferase -
  QYR57_RS05155 (QYR57_05155) dapB 1062019..1062786 (-) 768 WP_367561295.1 4-hydroxy-tetrahydrodipicolinate reductase -
  QYR57_RS05160 (QYR57_05160) - 1062803..1063655 (-) 853 Protein_990 DegV family protein -
  QYR57_RS05165 (QYR57_05165) - 1063662..1064036 (-) 375 Protein_991 DUF1149 family protein -
  QYR57_RS05170 (QYR57_05170) - 1064109..1064630 (-) 522 WP_003099873.1 hypothetical protein -
  QYR57_RS05175 (QYR57_05175) tnpA 1064827..1065300 (+) 474 WP_003099875.1 IS200/IS605 family transposase -
  QYR57_RS05180 (QYR57_05180) - 1065439..1066159 (-) 721 Protein_994 glucosaminidase domain-containing protein -
  QYR57_RS05185 (QYR57_05185) - 1066329..1066943 (-) 615 WP_016356029.1 glycoside hydrolase family 73 protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45237.91 Da        Isoelectric Point: 4.4847

>NTDB_id=852215 QYR57_RS05060 WP_367562083.1 1037307..1038536(-) (clpX) [Streptococcus iniae strain Si 4-21]
MAVNRTNDIKVHCSFCGKDQDEVKKIIAGNNVFICDECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVVGQDH
AKKALAVAVYNHYKRVSFTESRDEDEVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQATDYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTEASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDEDASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLTVADLIQI
LTEPRNALVKQYQALLSYDGVELEFEKVALEAIVAKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVIKVRITKDSVDG
LKKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=852215 QYR57_RS05060 WP_367562083.1 1037307..1038536(-) (clpX) [Streptococcus iniae strain Si 4-21]
ATGGCAGTTAATCGTACAAACGATATTAAGGTCCATTGTTCATTTTGTGGCAAGGACCAAGATGAAGTTAAAAAAATTAT
TGCAGGGAACAATGTTTTCATCTGTGATGAATGTGTTGCATTATCTCAAGAAATTATAAAAGAAGAATTAGCAGAGGAAG
TATTAGCTGATTTAACGGAAGTTCCAAAACCAAAAGAACTTTTAGATATTTTAAATCAATATGTTGTTGGTCAAGACCAT
GCTAAAAAGGCTTTAGCAGTAGCAGTTTATAACCATTATAAGCGTGTTTCGTTTACAGAAAGTCGCGATGAAGATGAAGT
GGAATTGCAAAAGTCAAATATTCTCATGATTGGCCCAACTGGTTCAGGAAAAACCTTCTTGGCACAAACTTTGGCAAAAA
GTTTAAATGTACCATTTGCCATTGCGGATGCTACTTCATTAACTGAAGCTGGCTATGTCGGCGAAGATGTTGAGAATATT
CTGCTAAAATTAATTCAAGCAACTGATTATAATGTAGAACGTGCAGAACGTGGCATTATTTATGTTGATGAAATTGATAA
AATTGCTAAAAAAGGGGAAAATGTTTCCATTACACGCGATGTCTCTGGTGAAGGTGTTCAACAAGCCCTGCTAAAAATTA
TTGAAGGCACAGAAGCAAGTGTTCCACCTCAAGGTGGACGTAAACACCCTAATCAAGAGATGATTCAAATTGATACGAAA
AATATTTTGTTCATCGTTGGTGGCGCTTTTGATGGCATTGAAGAAATTGTTAAACAGCGTCTTGGAGAAAAAATTATTGG
TTTTGGCCAAAATAGCCGTAAAATTGATGAAGATGCTTCATATATGCAAGAAATTATCGCAGAAGACATTCAAAAATTTG
GCCTTATTCCAGAATTTATTGGACGCTTACCTGTTGTTGCGGCCTTAGAACAGTTAACAGTTGCTGACCTGATTCAAATT
TTAACAGAACCAAGAAATGCTCTTGTTAAACAATACCAAGCTCTTTTATCTTATGATGGTGTTGAACTTGAATTTGAAAA
GGTCGCTTTGGAAGCTATTGTCGCAAAAGCTATAGAACGTAAAACTGGTGCGCGTGGCCTTCGTTCAATCATTGAAGAAA
CCATGCTTGACATTATGTTTGAAATCCCTAGTCAAGAAGATGTTATTAAGGTTCGCATTACTAAGGACTCTGTGGATGGG
CTTAAAAAACCTATTTTGGAAACGGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.286

100

0.873
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.393

97.555

0.56