Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   QYH60_RS05905 Genome accession   NZ_CP129292
Coordinates   1112093..1112794 (+) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis subsp. lactis strain KMGR2-43     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1107093..1117794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYH60_RS05890 (QYH60_05890) - 1109488..1110396 (+) 909 WP_058208331.1 diacylglycerol kinase family protein -
  QYH60_RS05895 (QYH60_05895) - 1110543..1111229 (+) 687 WP_004255158.1 amino acid ABC transporter permease -
  QYH60_RS05900 (QYH60_05900) - 1111229..1111963 (+) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  QYH60_RS05905 (QYH60_05905) mecA 1112093..1112794 (+) 702 WP_004255173.1 adaptor protein MecA Regulator
  QYH60_RS05910 (QYH60_05910) - 1112797..1114128 (+) 1332 WP_021722251.1 MraY family glycosyltransferase -
  QYH60_RS05915 (QYH60_05915) sufC 1114303..1115073 (+) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  QYH60_RS05920 (QYH60_05920) sufD 1115211..1116467 (+) 1257 WP_301536142.1 Fe-S cluster assembly protein SufD -
  QYH60_RS05925 (QYH60_05925) - 1116467..1117684 (+) 1218 WP_058208332.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=852093 QYH60_RS05905 WP_004255173.1 1112093..1112794(+) (mecA) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=852093 QYH60_RS05905 WP_004255173.1 1112093..1112794(+) (mecA) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97