Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LBA42_RS05075 Genome accession   NZ_CP145437
Coordinates   1017507..1018139 (-) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012507..1023139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS05045 (LBA42_05045) tig 1013539..1014822 (-) 1284 WP_000116465.1 trigger factor -
  LBA42_RS05050 (LBA42_05050) - 1014983..1015375 (-) 393 WP_000378125.1 tyrosine-type recombinase/integrase -
  LBA42_RS05055 (LBA42_05055) cbpG 1015677..1016267 (-) 591 Protein_1003 choline-binding protein CbpG -
  LBA42_RS05060 (LBA42_05060) - 1016348..1016587 (-) 240 WP_000754501.1 hypothetical protein -
  LBA42_RS05065 (LBA42_05065) - 1016737..1017342 (-) 606 Protein_1005 DNA alkylation repair protein -
  LBA42_RS05070 (LBA42_05070) - 1017264..1017506 (-) 243 Protein_1006 DNA alkylation repair protein -
  LBA42_RS05075 (LBA42_05075) vraR 1017507..1018139 (-) 633 WP_000698433.1 response regulator transcription factor Regulator
  LBA42_RS05080 (LBA42_05080) - 1018153..1019148 (-) 996 WP_000743657.1 sensor histidine kinase -
  LBA42_RS05085 (LBA42_05085) liaF 1019145..1019843 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  LBA42_RS05090 (LBA42_05090) fni 1019920..1020930 (-) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  LBA42_RS05095 (LBA42_05095) - 1020914..1021921 (-) 1008 WP_000562430.1 phosphomevalonate kinase -
  LBA42_RS05100 (LBA42_05100) mvaD 1021908..1022861 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=850730 LBA42_RS05075 WP_000698433.1 1017507..1018139(-) (vraR) [Streptococcus pneumoniae strain HAC 39-1996]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=850730 LBA42_RS05075 WP_000698433.1 1017507..1018139(-) (vraR) [Streptococcus pneumoniae strain HAC 39-1996]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41