Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V5G01_RS02085 Genome accession   NZ_CP145083
Coordinates   405554..407845 (-) Length   763 a.a.
NCBI ID   WP_047918640.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_D_2024     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 400554..412845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G01_RS02070 (V5G01_02075) - 400987..401589 (+) 603 WP_017147124.1 restriction endonuclease subunit S -
  V5G01_RS02075 (V5G01_02080) - 401615..402184 (+) 570 WP_225577397.1 restriction endonuclease subunit S -
  V5G01_RS02080 (V5G01_02085) - 402416..405514 (+) 3099 WP_003687844.1 type I restriction endonuclease subunit R -
  V5G01_RS02085 (V5G01_02090) clpC 405554..407845 (-) 2292 WP_047918640.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  V5G01_RS02090 (V5G01_02095) clpS 407847..408149 (-) 303 WP_010951037.1 ATP-dependent Clp protease adapter ClpS -
  V5G01_RS02095 (V5G01_02100) - 408394..408597 (+) 204 WP_002217533.1 cold-shock protein -
  V5G01_RS02100 (V5G01_02105) pmbA 408896..410227 (-) 1332 WP_003687847.1 metalloprotease PmbA -
  V5G01_RS02105 (V5G01_02110) yjgA 410381..410887 (+) 507 WP_017147123.1 ribosome biogenesis factor YjgA -
  V5G01_RS02110 (V5G01_02115) - 410934..411665 (+) 732 WP_003687850.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84273.16 Da        Isoelectric Point: 6.6960

>NTDB_id=850263 V5G01_RS02085 WP_047918640.1 405554..407845(-) (clpC) [Neisseria gonorrhoeae strain WHO_D_2024]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDAAVPNVLKLCGADLKAVSEQLAASVAENTPLIPDHLLDTVET
RPTLGFQRVIQRAMVHTQSAGKGLAEPLDVLVALMSETDSHAVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYFSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALADGLAHQIVNDD
IPDALKEAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTGGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVAETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINGRFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLNNMVYGQEDAIDALVSAVK
MSRSGLGLPDKPIGSFLFSGPTGVGKTEVAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHRLLDKKVEAEFTPALRKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLADGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=850263 V5G01_RS02085 WP_047918640.1 405554..407845(-) (clpC) [Neisseria gonorrhoeae strain WHO_D_2024]
ATGCTTGCCCCTGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCGCCGTGCCGAACGTCTTAAAACTCTGCGGTGCGGATTTAAAAG
CGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGACCACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTCATCCAGCGGGCGATGGTGCATACCCAATCGGCAGGCAAAGGCTTGGCCGAGCC
TTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACGCCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTTTTCAGACGGCATGGAC
GACGATAATGAGAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGATCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTGTGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGACGGTTTGGCACATCAAATCGTCAACGACGAC
ATTCCCGACGCGCTCAAAGAGGCCGAAGTGTACGCGCTGGATATGGGTTCGCTTTTGGCGGGCACAAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTATTCATCGACGAAATCCACA
CCATCATCGGCGCGGGCAGCACCGGCGGCGGCACAATGGACGCGTCCAACCTGCTCAAACCCGCATTGGCGAAAGGTTCA
TTGCGCTGTATCGGCGCAACCACTTACGACGAATACCGTACTATTTTTGACAAAGACCACGCCCTAAGCCGCCGCTTCCA
GAAAATCGACGTGGTCGAACCCACCGTTGCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTCGAAGCCTTCC
ACCAAGTCCGCTACACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCCCGCTACATCAACGGGCGCTTCCTGCCC
GACAAAGCCATCGACGTAATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCGCAAATCGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAGACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGGCCGCGATTTGAACAATATGGTTTACGGGCAGGAAGACGCCATCGACGCGCTGGTTTCCGCCGTCAAA
ATGTCGCGTTCGGGCTTGGGGCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCTACCGGCGTCGGCAAAAC
CGAAGTCGCCAAACAGCTTGCCTACTCAATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCACG
CCGTATCGCGACTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAG
CAGCCTCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCATCCAGATATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGATAACAACGGTAAGAGCGCCGATTTCCGCAACGTCATCCTGATCATGACCACCAACGCAGGCG
CAGAAAGCCTCAGCCGACCCAGCCTAGGCTTTACCGCCAAACGCGAGCGCGGCGACGAAATGCAGGCAATCAACAAACTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATCATCCCGTTTGCACCTTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCGGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACACCGGCATTGCGTAAAT
ACTTGGCAGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTCGCCGACGGCGGCTTTGTGCGGATAGACTGGGATGCGGCGAAAGAAGAAGC
CGTATTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

AAA lid domain (AAA_lid_9)

(356-452)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.881

100

0.408
  clpC Streptococcus mutans UA159

38.433

100

0.405
  clpC Bacillus subtilis subsp. subtilis str. 168

37.345

100

0.394
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.586

94.233

0.392