Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V5G11_RS02425 Genome accession   NZ_CP145071
Coordinates   477223..479514 (-) Length   763 a.a.
NCBI ID   WP_235243195.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_J_2024     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 472223..484514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G11_RS02415 - 472643..473854 (+) 1212 Protein_469 restriction endonuclease subunit S -
  V5G11_RS02420 (V5G11_02420) - 474085..477183 (+) 3099 WP_353403637.1 type I restriction endonuclease subunit R -
  V5G11_RS02425 (V5G11_02425) clpC 477223..479514 (-) 2292 WP_235243195.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  V5G11_RS02430 (V5G11_02430) clpS 479516..479818 (-) 303 WP_010951037.1 ATP-dependent Clp protease adapter ClpS -
  V5G11_RS02435 (V5G11_02435) - 480063..480266 (+) 204 WP_002217533.1 cold-shock protein -
  V5G11_RS02440 (V5G11_02440) pmbA 480565..481896 (-) 1332 WP_003687847.1 metalloprotease PmbA -
  V5G11_RS02445 (V5G11_02445) yjgA 482050..482556 (+) 507 WP_025455780.1 ribosome biogenesis factor YjgA -
  V5G11_RS02450 (V5G11_02450) - 482603..483316 (+) 714 WP_003706625.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84172.15 Da        Isoelectric Point: 7.0021

>NTDB_id=849984 V5G11_RS02425 WP_235243195.1 477223..479514(-) (clpC) [Neisseria gonorrhoeae strain WHO_J_2024]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDAAVPNVLKLCGADLKAVSEQLAASVAENTPLIPDHLLDTVET
RPTLGFQRVIQRAMVHTQSAGKGLAEPLDVLVALMSETDSHAVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYFSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVSGG
IPDALKEAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTGGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVAETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINGRFLP
DKAIDVMDEAGAAQRILPKSKRKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLNNMVYGQEDAIDALVSAVK
MSRSGLGLPDKPIGSFLFSGPTGVGKTEVAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHRLLDKKVEAEFTPALRKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLADGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=849984 V5G11_RS02425 WP_235243195.1 477223..479514(-) (clpC) [Neisseria gonorrhoeae strain WHO_J_2024]
ATGCTTGCCCCTGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCGCCGTGCCGAACGTCTTAAAACTCTGCGGTGCGGATTTAAAAG
CGGTGTCCGAACAACTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGACCACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTCATCCAGCGGGCGATGGTGCATACCCAATCGGCAGGCAAAGGCTTGGCCGAGCC
TTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACGCCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTTTTCAGACGGCATGGAC
GACGATAATGAGAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGCATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTGTGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAGCGGCGGC
ATTCCCGACGCGCTCAAAGAAGCCGAAGTGTACGCGCTGGATATGGGTTCGCTTTTGGCGGGTACGAAATACCGGGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTATTCATCGACGAAATCCACA
CCATCATCGGCGCGGGCAGCACCGGCGGCGGCACGATGGACGCGTCCAACCTGCTCAAACCCGCATTGGCGAAAGGTTCA
TTGCGCTGTATCGGCGCAACCACTTACGACGAATACCGTACTATTTTTGACAAAGACCACGCCCTAAGCCGCCGTTTCCA
GAAAATCGACGTGGTCGAACCCACCGTTGCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTCGAAGCCTTCC
ACCAAGTCCGCTACACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCCCGCTACATCAACGGGCGCTTCCTGCCC
GACAAAGCCATCGACGTAATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACGGAAAAAAGTCATCGG
CAAAGCGCAAATCGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAGACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGGCCGCGATTTGAACAATATGGTTTACGGGCAGGAAGACGCCATCGACGCGCTGGTTTCCGCCGTCAAA
ATGTCGCGTTCGGGCTTGGGGCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCTACCGGCGTCGGCAAAAC
CGAAGTCGCCAAACAGCTTGCCTACTCAATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCACG
CCGTATCGCGACTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAG
CAGCCTCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCATCCAGATATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGATAACAACGGTAAGAGCGCCGATTTCCGCAACGTCATCCTGATCATGACCACCAACGCAGGCG
CAGAAAGCCTCAGCCGACCCAGCCTAGGCTTTACCGCCAAACGCGAGCGCGGCGACGAAATGCAGGCAATCAACAAACTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATCATCCCGTTTGCACCTTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCGGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACACCGGCATTGCGTAAAT
ACTTGGCAGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTCGCCGACGGCGGCTTTGTGCGGATAGACTGGGATGCGGCGAAAGAAGAAGC
CGTATTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

AAA lid domain (AAA_lid_9)

(356-452)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.881

100

0.408
  clpC Streptococcus mutans UA159

38.433

100

0.405
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.725

94.233

0.393
  clpC Bacillus subtilis subsp. subtilis str. 168

37.221

100

0.393