Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V5G08_RS02085 Genome accession   NZ_CP145037
Coordinates   406849..409140 (-) Length   763 a.a.
NCBI ID   WP_003696850.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_O_2024     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 401849..414140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G08_RS02070 (V5G08_02075) - 402282..402884 (+) 603 WP_017147124.1 restriction endonuclease subunit S -
  V5G08_RS02075 (V5G08_02080) - 402910..403479 (+) 570 WP_225577397.1 restriction endonuclease subunit S -
  V5G08_RS02080 (V5G08_02085) - 403711..406809 (+) 3099 WP_003687844.1 type I restriction endonuclease subunit R -
  V5G08_RS02085 (V5G08_02090) clpC 406849..409140 (-) 2292 WP_003696850.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  V5G08_RS02090 (V5G08_02095) clpS 409142..409444 (-) 303 WP_010951037.1 ATP-dependent Clp protease adapter ClpS -
  V5G08_RS02095 (V5G08_02100) - 409689..409892 (+) 204 WP_002217533.1 cold-shock protein -
  V5G08_RS02100 (V5G08_02105) pmbA 410191..411522 (-) 1332 WP_003687847.1 metalloprotease PmbA -
  V5G08_RS02105 (V5G08_02110) yjgA 411676..412182 (+) 507 WP_017147123.1 ribosome biogenesis factor YjgA -
  V5G08_RS02110 (V5G08_02115) - 412229..412960 (+) 732 WP_003687850.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84301.22 Da        Isoelectric Point: 6.7907

>NTDB_id=849109 V5G08_RS02085 WP_003696850.1 406849..409140(-) (clpC) [Neisseria gonorrhoeae strain WHO_O_2024]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDAAVPNVLKLCGADLKAVSEQLAASVAENTPLIPDHLLDTVET
RPTLGFQRVIQRAMVHTQSAGKGLAEPLDVLVALMSETDSHAVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYFSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALADGLAHQIVNDD
IPDALKEAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTGGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVAETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINGRFLP
DKAIDVMDEAGAAQRILPKSKRKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLNNMVYGQEDAIDALVSAVK
MSRSGLGLPDKPIGSFLFSGPTGVGKTEVAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHRLLDKKVEAEFTPALRKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLADGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=849109 V5G08_RS02085 WP_003696850.1 406849..409140(-) (clpC) [Neisseria gonorrhoeae strain WHO_O_2024]
ATGCTTGCCCCTGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCGCCGTGCCGAACGTCTTAAAACTCTGCGGTGCGGATTTAAAAG
CGGTGTCCGAACAACTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGACCACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTCATCCAGCGGGCGATGGTGCATACCCAATCGGCAGGCAAAGGCTTGGCCGAGCC
TTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACGCCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTTTTCAGACGGCATGGAC
GACGATAATGAGAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGATCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTGTGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGACGGTTTGGCACATCAAATCGTCAACGACGAC
ATTCCCGACGCGCTCAAAGAGGCCGAAGTGTACGCGCTGGATATGGGTTCGCTTTTGGCGGGCACAAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTATTCATCGACGAAATCCACA
CCATCATCGGCGCGGGCAGCACCGGCGGCGGCACGATGGACGCGTCCAACCTGCTCAAACCCGCATTGGCGAAAGGTTCA
TTGCGCTGTATCGGCGCAACCACTTACGACGAATACCGTACTATTTTTGACAAAGACCACGCCCTAAGCCGCCGTTTCCA
GAAAATCGACGTGGTCGAACCCACCGTTGCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTCGAAGCCTTCC
ACCAAGTCCGCTACACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCCCGCTACATCAACGGGCGCTTCCTGCCC
GACAAAGCCATCGACGTAATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACGGAAAAAAGTCATCGG
CAAAGCGCAAATCGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAGACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGGCCGCGATTTGAACAATATGGTTTACGGGCAGGAAGACGCCATCGACGCGCTGGTTTCCGCCGTCAAA
ATGTCGCGTTCGGGCTTGGGGCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCTACCGGCGTCGGCAAAAC
CGAAGTCGCCAAACAGCTTGCCTACTCAATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCACG
CCGTATCGCGACTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAG
CAGCCTCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCATCCAGATATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGATAACAACGGTAAGAGCGCCGATTTCCGCAACGTCATCCTGATCATGACCACCAACGCAGGCG
CAGAAAGCCTCAGCCGACCCAGCCTAGGCTTTACCGCCAAACGCGAGCGCGGCGACGAAATGCAGGCAATCAACAAACTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATCATCCCGTTTGCACCTTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCGGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACACCGGCATTGCGTAAAT
ACTTGGCAGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTCGCCGACGGCGGCTTTGTGCGGATAGACTGGGATGCGGCGAAAGAAGAAGC
CGTATTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

AAA lid domain (AAA_lid_9)

(356-452)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.759

100

0.406
  clpC Streptococcus mutans UA159

38.433

100

0.405
  clpC Bacillus subtilis subsp. subtilis str. 168

37.221

100

0.393
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.586

94.233

0.392