Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V5G02_RS02440 Genome accession   NZ_CP145026
Coordinates   477669..479960 (-) Length   763 a.a.
NCBI ID   WP_003694941.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_S2_2024     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 472669..484960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G02_RS02430 (V5G02_02430) - 473076..474299 (+) 1224 WP_025456107.1 restriction endonuclease subunit S -
  V5G02_RS02435 (V5G02_02435) - 474531..477629 (+) 3099 WP_003692800.1 type I restriction endonuclease subunit R -
  V5G02_RS02440 (V5G02_02440) clpC 477669..479960 (-) 2292 WP_003694941.1 ATP-dependent Clp protease ATP-binding subunit ClpA Regulator
  V5G02_RS02445 (V5G02_02445) clpS 479962..480264 (-) 303 WP_010951037.1 ATP-dependent Clp protease adapter ClpS -
  V5G02_RS02450 (V5G02_02450) - 480509..480712 (+) 204 WP_002217533.1 cold-shock protein -
  V5G02_RS02455 (V5G02_02455) pmbA 481011..482342 (-) 1332 WP_003687847.1 metalloprotease PmbA -
  V5G02_RS02460 (V5G02_02460) yjgA 482496..483002 (+) 507 WP_025455780.1 ribosome biogenesis factor YjgA -
  V5G02_RS02465 (V5G02_02465) - 483049..483762 (+) 714 WP_003706625.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84345.22 Da        Isoelectric Point: 6.6057

>NTDB_id=848825 V5G02_RS02440 WP_003694941.1 477669..479960(-) (clpC) [Neisseria gonorrhoeae strain WHO_S2_2024]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDAAVPNVLKLCGADLKAVSEQLAASVAENTPLIPDHLLDTVET
RPTLGFQRVIQRAMVHTQSAGKGLAEPLDVLVALMSETDSHAVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYFSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALADGLAHQIVNDD
IPDALKEAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTGGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVAETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLNNMVYGQEDAIDALVSAVK
MSRSGLGLPDKPIGSFLFSGPTGVGKTEVAKQLAYSMGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHRLLDKKVEAEFTPALRKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLADGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=848825 V5G02_RS02440 WP_003694941.1 477669..479960(-) (clpC) [Neisseria gonorrhoeae strain WHO_S2_2024]
ATGCTTGCCCCTGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCGCCGTGCCGAACGTCTTAAAACTCTGCGGTGCGGATTTAAAAG
CGGTGTCCGAACAACTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGACCACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTCATCCAGCGGGCGATGGTGCATACCCAATCGGCAGGCAAAGGCTTGGCCGAGCC
TTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACGCCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTTTTCAGACGGCATGGAC
GACGATAATGAGAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGATCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTGTGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCAGGCGTGGGCAAAACCGCGCTGGCGGACGGTTTGGCACATCAAATCGTCAACGACGAC
ATTCCCGACGCGCTCAAAGAGGCCGAAGTGTACGCGCTGGATATGGGTTCGCTTTTGGCGGGCACAAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTATTCATCGACGAAATCCACA
CCATCATCGGCGCGGGCAGCACCGGCGGCGGCACGATGGACGCGTCCAACCTGCTCAAACCCGCATTGGCGAAAGGTTCA
TTGCGCTGTATCGGCGCAACCACTTACGACGAATACCGTACTATTTTTGACAAAGACCACGCCCTAAGCCGCCGCTTCCA
GAAAATCGACGTGGTCGAACCCACCGTTGCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTCGAAGCCTTCC
ACCAAGTCCGCTACACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCCCGCTACATCAACGAGCGCTTCCTGCCC
GACAAAGCCATCGACGTAATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCGCAAATCGAAACCGTCATCGCCAAAGTCGCGCGGATTCCCGAAAAGACCGTGTCGCACGACGACAAACAAGTGT
TGCAATTCCTCGGCCGCGATTTGAACAATATGGTTTACGGGCAGGAAGACGCCATCGACGCGCTGGTTTCCGCCGTCAAA
ATGTCGCGTTCGGGCTTGGGGCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCTACCGGCGTCGGCAAAAC
CGAAGTCGCCAAACAGCTTGCCTACTCAATGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCACG
CCGTATCGCGACTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAG
CAGCCTCATTGCGTGTTGCTCTTGGACGAAATCGAAAAAGCCCATCCAGATATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGATAACAACGGTAAGAGCGCCGATTTCCGCAACGTCATCCTGATCATGACCACCAACGCAGGCG
CAGAAAGCCTCAGCCGACCCAGCCTAGGCTTTACCGCCAAACGCGAGCGCGGCGACGAAATGCAGGCAATCAACAAACTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATCATCCCGTTTGCACCTTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCGGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACACCGGCATTGCGTAAAT
ACTTGGCAGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTCGCCGACGGCGGCTTTGTGCGGATAGACTGGGATGCGGCGAAAGAAGAAGC
CGTATTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-61)

AAA lid domain (AAA_lid_9)

(356-452)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-738)

ATPase family associated with various cellular activities (AAA) (AAA)

(216-348)

AAA domain (Cdc48 subfamily) (AAA_2)

(491-652)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

37.881

100

0.408
  clpC Streptococcus mutans UA159

38.308

100

0.404
  clpC Bacillus subtilis subsp. subtilis str. 168

37.345

100

0.394
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.586

94.233

0.392