Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V5G23_RS11575 Genome accession   NZ_CP144925
Coordinates   2308112..2308747 (+) Length   211 a.a.
NCBI ID   WP_003185124.1    Uniprot ID   Q65F45
Organism   Bacillus licheniformis strain CP13     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2303112..2313747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G23_RS11550 (V5G23_11550) - 2304226..2304612 (+) 387 WP_003185133.1 protein liaI -
  V5G23_RS11555 (V5G23_11555) - 2304633..2305316 (+) 684 WP_009329563.1 PspA/IM30 family protein -
  V5G23_RS11560 (V5G23_11560) - 2305422..2306285 (+) 864 WP_025807519.1 DUF4097 domain-containing protein -
  V5G23_RS11565 (V5G23_11565) liaF 2306316..2307047 (+) 732 WP_003185130.1 cell wall-active antibiotics response protein LiaF -
  V5G23_RS11570 (V5G23_11570) liaS 2307044..2308108 (+) 1065 WP_071583692.1 two-component system sensor histidine kinase LiaS -
  V5G23_RS11575 (V5G23_11575) vraR 2308112..2308747 (+) 636 WP_003185124.1 response regulator transcription factor Regulator
  V5G23_RS11580 (V5G23_11580) - 2308784..2309167 (-) 384 WP_003185122.1 hypothetical protein -
  V5G23_RS11585 (V5G23_11585) - 2309211..2310332 (-) 1122 WP_003185120.1 Ger(x)C family spore germination protein -
  V5G23_RS11590 (V5G23_11590) - 2310329..2311429 (-) 1101 WP_048349997.1 endospore germination permease -
  V5G23_RS11595 (V5G23_11595) - 2311398..2312840 (-) 1443 WP_048349996.1 spore germination protein -
  V5G23_RS11600 (V5G23_11600) - 2312964..2313131 (+) 168 WP_003185114.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.83 Da        Isoelectric Point: 5.1797

>NTDB_id=848140 V5G23_RS11575 WP_003185124.1 2308112..2308747(+) (vraR) [Bacillus licheniformis strain CP13]
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Nucleotide


Download         Length: 636 bp        

>NTDB_id=848140 V5G23_RS11575 WP_003185124.1 2308112..2308747(+) (vraR) [Bacillus licheniformis strain CP13]
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACGGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65F45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.052

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.389