Detailed information NTG0848049

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V5G22_RS19710
• Genome accession: NZ_CP144920
• Coordinates: 3825386..3827995 (-)
• Length: 869 a.a.
• NCBI ID: WP_011197985.1
• Uniprot ID: Q65JE2
• Organism: Bacillus licheniformis strain CP26
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 3820386..3832995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G22_RS19685 (V5G22_19685)	-	3821396..3821833 (-)	438	WP_011201654.1	hypothetical protein	-
V5G22_RS19690 (V5G22_19690)	-	3821889..3822137 (-)	249	WP_080508521.1	HNH/endonuclease VII fold putative polymorphic toxin	-
V5G22_RS19695 (V5G22_19695)	-	3822134..3822661 (-)	528	WP_003181977.1	pre-toxin TG domain-containing protein	-
V5G22_RS19700 (V5G22_19700)	-	3822843..3823124 (-)	282	WP_003181975.1	putative quinol monooxygenase	-
V5G22_RS19705 (V5G22_19705)	hexB	3823458..3825368 (-)	1911	WP_003181972.1	DNA mismatch repair endonuclease MutL	Machinery gene
V5G22_RS19710 (V5G22_19710)	hexA	3825386..3827995 (-)	2610	WP_011197985.1	DNA mismatch repair protein MutS	Machinery gene
V5G22_RS19715 (V5G22_19715)	cotE	3828106..3828654 (-)	549	WP_003181968.1	outer spore coat protein CotE	-
V5G22_RS19720 (V5G22_19720)	ymcA	3828897..3829328 (-)	432	WP_003181967.1	RicAFT regulatory complex protein RicA family protein	Regulator
V5G22_RS19725 (V5G22_19725)	miaB	3829330..3830859 (-)	1530	WP_003181965.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
V5G22_RS19730 (V5G22_19730)	-	3831003..3832178 (-)	1176	WP_003181962.1	glycine C-acetyltransferase	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98514.94 Da
• Isoelectric Point: 5.3661

>NTDB_id=848049 V5G22_RS19710 WP_011197985.1 3825386..3827995(-) (hexA) [Bacillus licheniformis strain CP26]
MAGYTPMIQQYLKIKAEYQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSSERIPMCGVPYHSCSSYIEQLIKK
GYKVAICEQVEDPKSAKGVVKREVVQLITPGTVMDGKGIHENENNFIASVSKFQHTYGLAFSDLTTGENLVTAIERLDDV
VSEIYSVGAREIVVSRNLDEKDVAMLKERCGATISFEDEQADEVPGIVNGLGSKELVDTFMRLYVYLKRTQKRSLDHLQN
VQAYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRKGQIEERQEIVETLIAHLF
EREDLRERLKEVYDLERLAGRVAYGNVNARDLIQLKESLKQVPAIKQLVGSLDHPKAKARAEKIDPCGDLLNLLEDALYE
NPPLSLKEGNLIKDGYHAKLDEYRDASKNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANIHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFSELRSKVKEYIPRLQQLAKMMSELDVLQCFATISENRHYVKPEF
SDDVVQVIDGRHPVVEKVMDSQSYVPNSCEMGKGRQMLLITGPNMSGKSTYMRQMALISILAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVHATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHEHIGAKTLFSTHYHEL
TSLEEKLDDLKNVHVRAEEYEGKVVFLHQIKEGAADKSYGIHVAQLAELPDGLISRAKTILKELESGAKEAAPSTAPNMV
KEAAEEAAATVADQPAQLSFFETDKPIEKETKLSKKEQAVLAEFKAMDLLDMTPIQVMNELYRLQKKLK

Nucleotide

• Length: 2610 bp

>NTDB_id=848049 V5G22_RS19710 WP_011197985.1 3825386..3827995(-) (hexA) [Bacillus licheniformis strain CP26]
ATGGCAGGCTACACGCCTATGATACAGCAATATTTAAAGATTAAGGCAGAGTATCAGGATGCCTTTTTATTTTTTCGTCT
TGGCGACTTTTATGAGATGTTTTTTGAAGATGCAAAAAAGGCGTCTCAGGAGCTCGAAATCACGCTGACGAGCAGGGACG
GAGGATCAAGCGAAAGAATTCCGATGTGCGGGGTTCCTTATCATTCCTGCTCTTCGTATATCGAACAGCTCATTAAAAAA
GGCTATAAAGTCGCGATCTGTGAACAGGTGGAGGACCCTAAATCGGCCAAAGGAGTCGTCAAAAGGGAAGTCGTGCAGCT
GATCACACCCGGCACCGTGATGGACGGCAAAGGGATTCATGAAAATGAAAACAACTTTATCGCCTCTGTCAGTAAATTTC
AGCATACATACGGGCTCGCTTTTTCTGATTTGACGACAGGCGAGAATTTAGTAACGGCTATCGAAAGGCTTGATGATGTC
GTTTCCGAAATTTACTCTGTCGGAGCAAGGGAAATCGTCGTCAGCCGCAACCTTGACGAGAAAGACGTCGCAATGCTGAA
AGAGCGCTGCGGCGCCACGATCTCTTTCGAGGATGAACAAGCGGATGAAGTGCCTGGCATTGTGAACGGACTGGGGTCCA
AAGAGCTTGTCGATACGTTTATGAGGCTTTACGTCTACTTGAAGCGGACGCAGAAAAGAAGCCTCGACCACCTTCAAAAC
GTTCAGGCCTACGAGCTCGAAGAAGCGATGAAAATCGATTTGTACTCGAAACGCAATCTTGAACTGACGGAAACGATCCG
TTCGAAAAACAAAAAAGGCTCGCTTCTTTGGCTTTTGGATGAAACGAAAACGGCCATGGGAGGGCGGCTGTTAAAGCAAT
GGATCGACAGGCCGCTGATCAGAAAGGGACAGATCGAAGAGCGCCAGGAAATCGTTGAAACGCTGATCGCCCATCTGTTT
GAGCGGGAAGATTTGCGCGAACGGCTGAAGGAAGTATACGACCTCGAGCGGCTCGCCGGAAGGGTCGCATACGGCAACGT
CAACGCCAGAGATTTGATCCAGCTGAAGGAATCGCTGAAACAAGTCCCGGCCATCAAACAGCTTGTCGGCTCCCTCGACC
ATCCGAAAGCAAAAGCGCGCGCCGAGAAAATCGATCCGTGCGGCGATCTTTTGAATCTTTTGGAAGACGCGCTATACGAG
AATCCGCCTCTTTCATTAAAAGAGGGGAACTTAATCAAAGACGGCTACCACGCGAAACTGGATGAATACAGGGACGCAAG
CAAGAACGGAAAAGACTGGATCGCAAGGCTTGAGCAGCAGGAACGCGAGTACACGGGAATCCGCTCTTTAAAAGTCGGCT
TTAACAAGGTGTTCGGCTATTATATTGAAGTGACGAAAGCGAACATCCATCTGCTTGAAGAAGGCCGCTATGAACGGAAG
CAGACGCTGACCAATGCAGAACGCTACATCACGCCGGAGCTGAAAGAAAAAGAAGCCCTGATTCTCGAAGCGGAAAACAA
TATTTGCGAGCTGGAGTATGAGCTGTTTTCCGAGCTTCGCAGCAAGGTGAAGGAATATATCCCGCGCTTGCAGCAGCTGG
CAAAAATGATGAGCGAGCTTGATGTGCTCCAATGTTTTGCGACGATCAGCGAAAACCGGCACTATGTTAAGCCGGAGTTT
TCCGATGATGTCGTTCAGGTGATCGACGGACGGCATCCGGTCGTAGAAAAGGTGATGGACAGCCAGTCTTACGTTCCGAA
CAGCTGTGAAATGGGCAAAGGCAGGCAGATGCTTTTAATCACCGGGCCGAATATGTCCGGGAAAAGCACGTATATGAGAC
AGATGGCGCTGATCTCCATTTTGGCGCAGATCGGCTGCTTTGTTCCTGCGAAAAAAGCGGTGCTGCCGATCTTTGATCAG
ATCTTTACGAGAATTGGCGCAGCGGATGATCTTATATCCGGACAGAGCACGTTTATGGTGGAAATGCTTGAAGCCAAAAA
CGCGATCGTCCATGCGACGAAAAACAGCTTGATTTTATTTGACGAAATCGGCCGGGGTACGTCCACTTACGACGGAATGG
CGCTTGCACAAGCGATCATCGAGTACGTTCACGAGCACATCGGCGCGAAGACTTTATTTTCCACTCACTACCACGAGCTG
ACGTCCCTTGAAGAAAAGCTGGACGATTTGAAGAATGTCCACGTTCGTGCGGAAGAATACGAAGGAAAGGTCGTTTTCCT
TCACCAGATAAAAGAAGGAGCAGCAGATAAAAGCTACGGTATCCATGTCGCGCAGCTGGCTGAATTGCCCGACGGTTTGA
TCAGCAGGGCGAAAACGATCCTGAAAGAACTTGAATCCGGCGCAAAAGAAGCCGCTCCATCAACGGCACCGAATATGGTA
AAAGAGGCGGCGGAAGAAGCCGCGGCGACTGTTGCAGATCAACCGGCCCAGCTGTCATTTTTTGAGACGGACAAGCCAAT
AGAAAAAGAGACGAAGCTCTCCAAAAAAGAGCAGGCTGTTTTAGCCGAATTTAAAGCGATGGATCTGCTCGATATGACGC
CTATACAAGTCATGAATGAACTGTACAGGCTGCAAAAAAAATTAAAGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

• MutS family domain IV (MutS_IV) (415-506)

3D structure

• AlphaFold DB: Q65JE2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.017	99.54	0.488
mutS	Pseudomonas stutzeri strain ATCC 17587	37.528	100	0.381