Detailed information NTG0847548

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V4939_RS12295
• Genome accession: NZ_CP144733
• Coordinates: 2736032..2738302 (-)
• Length: 756 a.a.
• NCBI ID: WP_012701386.1
• Uniprot ID: C1DKZ7
• Organism: Azotobacter vinelandii DJ
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2731032..2743302

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V4939_RS12275 (V4939_12275)	trxB	2733164..2734111 (+)	948	WP_012701383.1	thioredoxin-disulfide reductase	-
V4939_RS12280 (V4939_12280)	aat	2734163..2734843 (+)	681	WP_012701384.1	leucyl/phenylalanyl-tRNA--protein transferase	-
V4939_RS12285 (V4939_12285)	-	2734923..2735630 (+)	708	WP_041807228.1	arginyltransferase	-
V4939_RS12290 (V4939_12290)	infA	2735733..2735951 (+)	219	WP_002553999.1	translation initiation factor IF-1	-
V4939_RS12295 (V4939_12295)	clpC	2736032..2738302 (-)	2271	WP_012701386.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
V4939_RS12300 (V4939_12300)	clpS	2738332..2738694 (-)	363	WP_012701387.1	ATP-dependent Clp protease adapter ClpS	-
V4939_RS12305 (V4939_12305)	cspD	2738924..2739202 (+)	279	WP_338459944.1	cold shock domain-containing protein CspD	-
V4939_RS12310 (V4939_12310)	-	2739771..2741996 (+)	2226	WP_012701390.1	NADP-dependent isocitrate dehydrogenase	-
V4939_RS12315 (V4939_12315)	-	2742426..2742590 (+)	165	WP_012701392.1	hypothetical protein	-
V4939_RS12320 (V4939_12320)	-	2742627..2742860 (+)	234	WP_041807230.1	hypothetical protein	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83689.27 Da
• Isoelectric Point: 5.9049

>NTDB_id=847548 V4939_RS12295 WP_012701386.1 2736032..2738302(-) (clpC) [Azotobacter vinelandii DJ]
MLNRELEVTLNLAFKEARAKRHEFMTVEHLLLALLDNEAAAAVLRACGANIDKLRHDLQEFIDSTTPLIPQHDEERETQP
TLGFQRVLQRAVFHVQSSGKREVTGANVLVAIFSEQESQAVFLLKQQSVARIDVVNYIAHGISKVPGHGDHPDGEHEMQD
EEGGDASASGHPLEAYASNLNELARQGRIDPLVGREFEVERVAQILARRRKNNPLLVGEAGVGKTAIAEGLAKRIVDNQV
PDLLTHSVVYSLDLGALLAGTKYRGDFEKRFKALLNELRKKPHAILFIDEIHTIIGAGAASGGVMDASNLLKPLLSSGEI
RCIGSTTFQEFRGIFEKDRALARRFQKVDVIEPSVEDTVGILRGLKPRFEQHHGIEYSDEALRAAAELSFRYINDRHMPD
KAIDVIDEAGAFQRLQPEDRRAKLIDVAQVEDIVAKIARIPPKHVSTSDKELLRNLERDLKLTVFGQDAAIDSLATAIKL
SRAGLKSPDKPVGSFLFAGPTGVGKTEAARQLAKALGVELVRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTEAITKQ
PHCVLLLDEIEKAHPEVFNLLLQVMDHGTLTDNNGRKADFRSVIIIMTTNAGAETAARASIGFTLQDHSSDAMEVIKKSF
TPEFRNRLDTIIQFGRLSHEVIKNIVDKFLTELQAQLEDKHVQLDVSERARGWLAEHGYDAQMGARPMARLIQDRIKRPL
AEEILFGELAEHGGVVHIDLEGEELSFDFETAAEVA

Nucleotide

• Length: 2271 bp

>NTDB_id=847548 V4939_RS12295 WP_012701386.1 2736032..2738302(-) (clpC) [Azotobacter vinelandii DJ]
ATGTTGAACCGTGAGCTCGAAGTCACTCTCAATCTTGCCTTCAAGGAGGCTCGTGCAAAACGTCATGAGTTCATGACGGT
GGAGCACCTCCTGCTGGCGCTTCTGGACAACGAAGCCGCGGCTGCCGTACTGCGGGCCTGCGGTGCGAATATCGACAAGC
TCCGGCATGACTTGCAGGAGTTCATCGACTCCACGACTCCTCTGATTCCACAGCACGATGAAGAGCGTGAGACCCAGCCT
ACCCTCGGCTTCCAGAGGGTGCTGCAGCGCGCGGTCTTTCATGTGCAGAGTTCTGGTAAGCGGGAAGTGACCGGAGCCAA
CGTGCTCGTGGCCATCTTCAGCGAACAGGAAAGCCAGGCCGTCTTTCTGCTCAAGCAGCAGAGTGTGGCTCGTATAGACG
TGGTGAACTACATTGCTCATGGCATTTCCAAAGTGCCGGGTCATGGCGATCATCCTGATGGCGAGCATGAGATGCAGGAC
GAAGAGGGTGGAGACGCTTCGGCTTCCGGTCATCCCCTGGAGGCCTATGCGAGCAATCTGAACGAACTGGCTCGTCAGGG
GCGGATCGATCCGCTGGTCGGGCGTGAGTTCGAGGTCGAGCGGGTCGCGCAGATCCTGGCCCGGCGGCGCAAGAACAATC
CTCTGCTGGTGGGCGAGGCCGGGGTCGGCAAAACGGCCATCGCCGAAGGATTGGCGAAACGCATCGTCGACAATCAGGTT
CCGGATCTTCTGACGCACAGCGTCGTGTACTCCCTCGACCTCGGGGCATTGCTCGCCGGTACCAAATATCGCGGTGACTT
CGAGAAGCGCTTCAAGGCATTGCTCAATGAGTTGCGCAAGAAGCCGCATGCCATCCTGTTCATCGACGAGATCCACACCA
TCATAGGCGCCGGTGCCGCCTCCGGCGGTGTGATGGATGCCTCGAACCTGCTCAAGCCGCTTCTCTCGTCCGGAGAGATC
CGCTGCATCGGTTCGACCACCTTCCAGGAGTTCCGCGGCATCTTCGAGAAGGATCGGGCCTTGGCGCGTCGTTTCCAGAA
GGTCGATGTGATCGAGCCTTCGGTCGAGGATACCGTGGGTATCCTTCGCGGGCTCAAGCCGCGTTTCGAGCAGCACCATG
GCATCGAGTACAGCGATGAGGCGCTGCGGGCCGCAGCGGAGCTGTCCTTTCGCTATATCAACGATCGCCACATGCCTGAC
AAAGCCATCGATGTTATCGACGAGGCAGGTGCCTTCCAGCGTCTCCAGCCGGAGGACCGGCGTGCCAAGCTTATCGATGT
GGCTCAGGTCGAGGATATCGTTGCCAAGATCGCTCGTATTCCGCCCAAACATGTTTCCACTTCCGACAAGGAACTGCTGC
GTAATCTCGAGCGCGATCTCAAGTTGACCGTATTCGGTCAGGATGCCGCTATCGATTCGCTCGCCACGGCAATCAAGTTG
TCGCGGGCTGGCTTGAAGTCACCGGACAAGCCGGTCGGTTCCTTCCTCTTCGCCGGTCCCACCGGGGTGGGCAAGACCGA
GGCGGCCCGGCAGTTGGCCAAGGCGCTGGGTGTGGAGCTGGTGCGTTTCGACATGTCCGAGTACATGGAGCGGCACACGG
TTTCGCGGCTGATCGGCGCGCCTCCGGGATACGTCGGGTTCGATCAGGGGGGGCTGCTGACCGAGGCGATTACCAAGCAG
CCGCATTGCGTGCTGTTGCTGGATGAAATCGAGAAGGCGCACCCCGAGGTGTTCAATCTGCTATTGCAGGTCATGGACCA
TGGCACGCTGACCGACAACAACGGGCGCAAGGCTGATTTCCGCAGTGTCATCATCATCATGACCACCAATGCCGGGGCGG
AAACCGCGGCCCGTGCCTCGATCGGCTTTACTCTGCAGGATCATTCTTCCGATGCTATGGAGGTGATCAAGAAGAGCTTC
ACTCCCGAGTTCCGCAACCGTTTGGATACCATTATCCAGTTCGGTCGCCTGAGTCACGAGGTGATCAAGAATATCGTCGA
CAAGTTCCTTACCGAACTTCAGGCGCAACTGGAAGACAAGCACGTACAGCTGGATGTTTCCGAGCGGGCTCGTGGTTGGC
TCGCCGAGCATGGATATGATGCTCAGATGGGCGCGCGGCCGATGGCTCGCCTGATTCAGGACAGGATCAAGCGTCCCCTG
GCCGAGGAAATTCTCTTCGGTGAGTTGGCCGAGCATGGGGGAGTGGTGCATATCGATCTGGAGGGTGAGGAGCTTTCCTT
CGACTTCGAGACGGCAGCCGAAGTGGCTTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (215-328)

• AAA lid domain (AAA_lid_9) (354-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

• AAA domain (Cdc48 subfamily) (AAA_2) (490-651)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (657-737)

3D structure

• AlphaFold DB: C1DKZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	39.535	100	0.427
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.724	96.693	0.403
clpC	Streptococcus pneumoniae Rx1	38.413	100	0.403
clpC	Streptococcus pneumoniae TIGR4	38.413	100	0.403
clpC	Streptococcus pneumoniae D39	38.413	100	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.247	100	0.39
clpC	Streptococcus mutans UA159	45.338	82.275	0.373
clpC	Lactococcus lactis subsp. cremoris KW2	45.199	79.894	0.361