Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLA22_RS07655 Genome accession   NZ_CP128421
Coordinates   1526081..1527553 (-) Length   490 a.a.
NCBI ID   WP_021211938.1    Uniprot ID   -
Organism   Lactococcus cremoris strain A.2.2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1521081..1532553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLA22_RS07635 (LLA22_07680) murG 1521394..1522467 (-) 1074 WP_015082641.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LLA22_RS07640 (LLA22_07685) murD 1522710..1524059 (-) 1350 WP_015082642.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLA22_RS07645 (LLA22_07690) - 1524228..1524569 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLA22_RS07650 (LLA22_07695) - 1524654..1525895 (-) 1242 WP_015082643.1 ammonium transporter -
  LLA22_RS07655 (LLA22_07700) covS 1526081..1527553 (-) 1473 WP_021211938.1 HAMP domain-containing histidine kinase Regulator
  LLA22_RS07660 (LLA22_07705) covR 1527566..1528258 (-) 693 WP_015082645.1 response regulator transcription factor Regulator
  LLA22_RS07665 (LLA22_07710) - 1528414..1528944 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLA22_RS07670 (LLA22_07715) - 1529077..1529322 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLA22_RS07675 (LLA22_07720) - 1529646..1530008 (-) 363 Protein_1493 TIGR02328 family protein -
  LLA22_RS07680 (LLA22_07725) - 1530156..1530707 (+) 552 WP_021214392.1 Ltp family lipoprotein -
  LLA22_RS07685 (LLA22_07730) - 1530815..1531585 (+) 771 WP_015082647.1 hypothetical protein -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55891.76 Da        Isoelectric Point: 4.7018

>NTDB_id=847422 LLA22_RS07655 WP_021211938.1 1526081..1527553(-) (covS) [Lactococcus cremoris strain A.2.2]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=847422 LLA22_RS07655 WP_021211938.1 1526081..1527553(-) (covS) [Lactococcus cremoris strain A.2.2]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACTGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947