Detailed information NTG0847120

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: VM636_RS13365
• Genome accession: NZ_CP144555
• Coordinates: 3079808..3080932 (+)
• Length: 374 a.a.
• NCBI ID: WP_030421973.1
• Uniprot ID: A0A940XMH0
• Organism: Streptomyces sp. SCSIO 75703
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3074808..3085932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VM636_RS13350 (VM636_13350)	-	3075158..3076027 (+)	870	WP_030421976.1	hypothetical protein	-
VM636_RS13355 (VM636_13355)	-	3076085..3077839 (-)	1755	WP_030421975.1	BACON domain-containing protein	-
VM636_RS13360 (VM636_13360)	radA	3078316..3079725 (+)	1410	WP_030421974.1	DNA repair protein RadA	Machinery gene
VM636_RS13365 (VM636_13365)	disA	3079808..3080932 (+)	1125	WP_030421973.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
VM636_RS13370 (VM636_13370)	-	3080972..3081814 (-)	843	WP_199809427.1	hypothetical protein	-
VM636_RS13375 (VM636_13375)	-	3081989..3082639 (+)	651	WP_199809426.1	phosphatase PAP2 family protein	-
VM636_RS13380 (VM636_13380)	-	3082957..3083934 (+)	978	WP_030421970.1	A/G-specific adenine glycosylase	-
VM636_RS13385 (VM636_13385)	-	3084206..3084745 (+)	540	WP_030421969.1	SigE family RNA polymerase sigma factor	-
VM636_RS13390 (VM636_13390)	-	3084802..3085386 (+)	585	WP_037859013.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40170.95 Da
• Isoelectric Point: 5.0127

>NTDB_id=847120 VM636_RS13365 WP_030421973.1 3079808..3080932(+) (disA) [Streptomyces sp. SCSIO 75703]
MAANDRAAAPGKSGQSAGAEGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEVMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVSQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALTELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=847120 VM636_RS13365 WP_030421973.1 3079808..3080932(+) (disA) [Streptomyces sp. SCSIO 75703]
GTGGCAGCCAACGACCGGGCAGCGGCTCCCGGAAAGTCCGGCCAGAGCGCCGGCGCGGAGGGCCTGATGCGCGCCTCGCT
GAGCGCCGTCGCACCCGGAACGGCCCTGCGTGACGGCCTGGAGCGGGTCCTGCGCGGCAACACGGGCGGTCTGATCGTGC
TCGGCTCGGACAAGACCGTCGAGGTCATGTGCACGGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACACGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTCCAGCTCGTCCC
GGACCCGACGATCCCCACCGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAACAGGTCGGCTTCCCCG
TCGTCTCCGTCTCCCAGTCCATGCGGCTCATCGCCCTCTACGTGGACGGGCAGCGCCGCGTCCTGGAGGACTCCGCGGCG
ATCCTGTCCCGGGCGAACCAGGCCCTGGCGACCCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTCTCGGCGGTCTCCCAGCGCCTGGAGATGGTCCGCCGCATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGCCTGCTCGCCCTCCAGCTCGACGAACTGATCGCC
GGCGTCGAACCGGAACGCGAGCTGGTGGTGCGGGACTACGTGCCCGAGCCGACCGCCAAGCGCTCGCGCACCGTGGAGGA
GGCGCTGACCGAGCTGGACAAGCTCAGCCACGCCGAGTTGCTCGAACTGTCCACGGTGGCCCGCGCCCTGGGGTACACCG
GCTCGCCCGAGACGCTCGACTCGGCGGTCTCGCCGCGCGGTTTCCGGCTGCTGGCGAAGGTCCCCCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGACTGCAGAAGCTCCTCGCCGCCAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGACTCTCCCGCCTGGCCGAGTCCTCCATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

3D structure

• AlphaFold DB: A0A940XMH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447