Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   P3L48_RS19270 Genome accession   NZ_CP128196
Coordinates   3880083..3881165 (-) Length   360 a.a.
NCBI ID   WP_066385505.1    Uniprot ID   A0A3Q9QWG4
Organism   Neobacillus mesonae strain NS-6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3875083..3886165
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3L48_RS19225 - 3875653..3875895 (-) 243 WP_066385429.1 DUF2626 domain-containing protein -
  P3L48_RS19230 - 3875980..3876675 (-) 696 WP_066385431.1 helix-turn-helix domain-containing protein -
  P3L48_RS19235 - 3876889..3877077 (-) 189 WP_286229139.1 YqzE family protein -
  P3L48_RS19240 comGG 3877140..3877523 (-) 384 WP_286229141.1 competence type IV pilus minor pilin ComGG -
  P3L48_RS19245 comGF 3877520..3877999 (-) 480 WP_286232350.1 competence type IV pilus minor pilin ComGF -
  P3L48_RS19250 - 3877950..3878288 (-) 339 WP_286229143.1 hypothetical protein -
  P3L48_RS19255 comGD 3878272..3878712 (-) 441 WP_286229144.1 competence type IV pilus minor pilin ComGD -
  P3L48_RS19260 comGC 3878712..3879044 (-) 333 WP_066385444.1 competence type IV pilus major pilin ComGC Machinery gene
  P3L48_RS19265 comGB 3879065..3880102 (-) 1038 WP_350267719.1 competence type IV pilus assembly protein ComGB -
  P3L48_RS19270 comGA 3880083..3881165 (-) 1083 WP_066385505.1 competence type IV pilus ATPase ComGA Machinery gene
  P3L48_RS19275 - 3881292..3882269 (-) 978 WP_286229145.1 ROK family glucokinase -
  P3L48_RS19280 - 3882276..3882485 (-) 210 WP_066385506.1 YqgQ family protein -
  P3L48_RS19285 - 3882683..3883510 (+) 828 WP_286229146.1 hypothetical protein -
  P3L48_RS19290 - 3883473..3885035 (-) 1563 WP_286229147.1 rhomboid family intramembrane serine protease -
  P3L48_RS19295 - 3885145..3885336 (-) 192 WP_066385508.1 hypothetical protein -

Sequence

Protein


Download         Length: 360 a.a.        Molecular weight: 40377.64 Da        Isoelectric Point: 7.7492

>NTDB_id=846678 P3L48_RS19270 WP_066385505.1 3880083..3881165(-) (comGA) [Neobacillus mesonae strain NS-6]
MFPIVSEIEILANRIITDAARNQATDIHIIPRKNDTLVQIRLTNKLIPRLSLPKDECDRLISHFKFTANMDIGERRRPQS
GAIVCDVNGQLMGLRLSTLPSNNRESLVIRLLPQQDQIPFHQLSLFPSMTRKLLALLKHAHGLIIFTGPTGSGKTTTLYS
LLNETAHLFHRNVITLEDPVEKNYDSVLQVQVNEKAGVTYAAGLKAILRHDPDIIMVGEIRDAETAKIAVRAALTGHLVL
STMHTRDAKGAVFRLEEFGVNWLEVEQTLIAVTAQRLVELTCPFCEGECPPHCYSGGRWKRASVFELLSGRNLSAIMRAA
MGEKIDTNYRTLKDVIRKGIALGYIQSSEYDRLVYDDEET

Nucleotide


Download         Length: 1083 bp        

>NTDB_id=846678 P3L48_RS19270 WP_066385505.1 3880083..3881165(-) (comGA) [Neobacillus mesonae strain NS-6]
GTGTTTCCAATTGTTAGTGAAATTGAAATTTTAGCTAACAGAATTATTACTGATGCGGCAAGAAACCAGGCGACAGATAT
TCACATTATTCCTCGTAAGAATGACACCCTAGTGCAAATTAGGTTAACAAACAAACTGATTCCTCGATTATCACTTCCGA
AAGATGAATGCGACAGATTGATTTCCCATTTTAAATTTACAGCAAATATGGATATCGGAGAACGCAGACGCCCGCAGAGC
GGTGCGATTGTTTGTGATGTTAACGGACAACTAATGGGTCTAAGGCTGTCTACCCTTCCTTCAAACAACAGAGAAAGCCT
TGTCATTCGCCTATTGCCGCAGCAAGATCAAATTCCTTTTCACCAGCTCTCACTCTTTCCATCGATGACACGTAAATTAT
TAGCTTTGCTCAAACATGCACATGGTTTAATTATTTTCACTGGGCCAACTGGGTCTGGGAAAACCACGACCTTGTATTCA
CTTTTAAACGAAACTGCACACCTGTTCCATCGTAATGTGATTACTCTTGAAGACCCAGTTGAAAAAAATTATGATTCGGT
TCTCCAGGTTCAGGTAAATGAAAAAGCGGGGGTGACTTATGCTGCAGGTTTAAAAGCAATTCTTCGACATGATCCGGATA
TTATAATGGTCGGGGAAATCAGGGATGCGGAAACTGCAAAAATTGCCGTCCGCGCAGCTTTAACAGGTCATTTAGTTTTA
AGCACAATGCATACCCGCGATGCGAAAGGTGCGGTCTTTCGTTTGGAGGAGTTTGGCGTAAACTGGTTAGAGGTGGAACA
AACTTTAATTGCCGTCACCGCACAAAGATTAGTTGAATTAACCTGCCCATTTTGTGAAGGCGAATGCCCACCGCATTGTT
ATTCAGGCGGCAGGTGGAAAAGAGCAAGTGTGTTTGAACTGTTATCCGGAAGAAATTTATCTGCCATAATGAGAGCGGCA
ATGGGAGAAAAGATTGACACAAATTATCGGACATTAAAAGATGTGATTAGAAAAGGGATTGCGCTAGGCTATATTCAATC
CTCTGAATATGACCGGCTGGTGTATGATGATGAAGAAACATAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(14-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q9QWG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Bacillus subtilis subsp. subtilis str. 168

55.899

98.889

0.553
  pilB Glaesserella parasuis strain SC1401

39.548

98.333

0.389
  pilB Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

36.533

100

0.381