Detailed information NTG0084623

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ST1232TP_RS08140
• Genome accession: NZ_AP024311
• Coordinates: 1686280..1688481 (-)
• Length: 733 a.a.
• NCBI ID: WP_001807826.1
• Uniprot ID: A0AAP7YX23
• Organism: Staphylococcus aureus strain THI2018-120
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1681280..1693481

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1232TP_RS08125 (THI2018120TP_15700)	lepA	1682784..1684607 (-)	1824	WP_000368338.1	translation elongation factor 4	-
ST1232TP_RS08130 (THI2018120TP_15710)	rpsT	1684953..1685204 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
ST1232TP_RS08135 (THI2018120TP_15720)	holA	1685249..1686223 (-)	975	WP_001282570.1	DNA polymerase III subunit delta	-
ST1232TP_RS08140 (THI2018120TP_15730)	comEC	1686280..1688481 (-)	2202	WP_001807826.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ST1232TP_RS08145 (THI2018120TP_15740)	-	1688486..1688947 (-)	462	WP_000439690.1	ComE operon protein 2	-
ST1232TP_RS08150 (THI2018120TP_15750)	comEA	1689039..1689725 (-)	687	WP_001825349.1	ComEA family DNA-binding protein	Machinery gene
ST1232TP_RS08155 (THI2018120TP_15760)	-	1689765..1690481 (-)	717	WP_000084838.1	class I SAM-dependent methyltransferase	-
ST1232TP_RS08160 (THI2018120TP_15770)	rsfS	1690484..1690837 (-)	354	WP_001088020.1	ribosome silencing factor	-
ST1232TP_RS08165 (THI2018120TP_15780)	yqeK	1690838..1691422 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ST1232TP_RS08170 (THI2018120TP_15790)	nadD	1691412..1691981 (-)	570	WP_000725164.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
ST1232TP_RS08175 (THI2018120TP_15800)	yhbY	1691984..1692274 (-)	291	WP_000955234.1	ribosome assembly RNA-binding protein YhbY	-
ST1232TP_RS08180 (THI2018120TP_15810)	aroE	1692278..1693084 (-)	807	WP_000666746.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84968.25 Da
• Isoelectric Point: 10.0424

>NTDB_id=84623 ST1232TP_RS08140 WP_001807826.1 1686280..1688481(-) (comEC) [Staphylococcus aureus strain THI2018-120]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNPQFNERVQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVIDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFVFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGLLSNLIFVPYYSIILFPLSILFFITSHFIVGLMPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVINDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGELEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNVKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=84623 ST1232TP_RS08140 WP_001807826.1 1686280..1688481(-) (comEC) [Staphylococcus aureus strain THI2018-120]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATCCTCAGTTTAATGAGCGTGTTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTATTGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGTCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGAATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTCTTAATTTATCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCAAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAGCTATTAGCATTTGTATTTATAATTATGTTTATTTTGAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTATTATCTAATTTGATTTTTGTACCATACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAATGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACGAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTAATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAATTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTATAACGTTAAACTTATGGATGTAAGGCAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTTCTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGAAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGCCAACAAAACGGTCAAGTTACAATAGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (183-441)

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.226	100	0.982
comEC	Staphylococcus aureus MW2	97.817	100	0.978