Detailed information NTG0084610

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ST1232TP_RS04805
• Genome accession: NZ_AP024311
• Coordinates: 994162..995148 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959279.1
• Uniprot ID: A0A2S6DCY7
• Organism: Staphylococcus aureus strain THI2018-120
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 989162..1000148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1232TP_RS04785 (THI2018120TP_09160)	-	989530..991152 (+)	1623	WP_000406183.1	peptide ABC transporter substrate-binding protein	-
ST1232TP_RS04790 (THI2018120TP_09170)	trpS	991272..992261 (-)	990	WP_183137419.1	tryptophan--tRNA ligase	-
ST1232TP_RS04795 (THI2018120TP_09180)	spxA	992556..992951 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ST1232TP_RS04800 (THI2018120TP_09190)	mecA	993322..994041 (+)	720	WP_001217731.1	adaptor protein MecA	-
ST1232TP_RS04805 (THI2018120TP_09200)	coiA	994162..995148 (+)	987	WP_000959279.1	competence protein CoiA	Machinery gene
ST1232TP_RS04810 (THI2018120TP_09210)	pepF	995196..997004 (+)	1809	WP_000082727.1	oligoendopeptidase F	-
ST1232TP_RS04815 (THI2018120TP_09220)	yjbH	997464..998270 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ST1232TP_RS04820 (THI2018120TP_09230)	-	998293..998658 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ST1232TP_RS04825 (THI2018120TP_09240)	-	998762..999355 (-)	594	WP_000224612.1	CYTH domain-containing protein	-
ST1232TP_RS04830 (THI2018120TP_09250)	-	999541..999888 (+)	348	WP_001242104.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38800.32 Da
• Isoelectric Point: 9.4277

>NTDB_id=84610 ST1232TP_RS04805 WP_000959279.1 994162..995148(+) (coiA) [Staphylococcus aureus strain THI2018-120]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPISYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKRNVKMSELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGESILVSDNLNYFKLKKFIVALESKTAIIEKLINNYLNISSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=84610 ST1232TP_RS04805 WP_000959279.1 994162..995148(+) (coiA) [Staphylococcus aureus strain THI2018-120]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTTCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGTCAAAATGAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAATTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAGAAAGCATATTAGTAAGTGACAATCTTAATTATTTTAAACTGAAAA
AGTTTATTGTTGCTCTAGAAAGTAAAACAGCGATTATAGAAAAACTTATTAACAATTATTTAAATATTAGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A2S6DCY7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	96.037	100	0.96
coiA	Staphylococcus aureus MW2	96.037	100	0.96